Temporal patterns of recovery across eating disorder subtypes.
Temporal patterns of recovery across eating disorder subtypes.
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饮食失调亚型恢复的时间模式。
DOI：
10.1080/00048670701787610
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Mitchell,
中科院分区：
文献类型：
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作者：
VonHolle,Ann;Pinheiro,AndreaPoyastro;Thornton,LauraM;Klump,KellyL;Berrettini,WadeH;Brandt,Harry;Crawford,Steven;Crow,Scott;Fichter,ManfredM;Halmi,KatherineA;Johnson,Craig;Kaplan,AllanS;Keel,Pamela;LaVia,Maria;Mitchell,
目的：比较神经性厌食症（anorexia nervosa，AN）和神经性贪食症（bulimia nervosa，BN）指数发作个体的恢复模式。方法：采用Kaplan-Meier方法和考克斯比例风险模型，以进食障碍发作时间为条件进行比较，包括3年无症状的保守恢复标准。数据收集是回顾性的，从两个国际价格基金会遗传研究901个人与饮食disorders.Results：使用Kaplan-Meier方法，11%的人与指数AN和10%的人与指数BN符合恢复标准，在10年。15年时，16%的AN指数患者和25%的BN指数患者符合恢复标准。在一个考克斯比例风险模型的指数BN组有三倍的恢复率在10-14年（p=0.01）比指数AN group.Conclusions：最初的恢复概率是更大的那些指数AN，但作为饮食失调的持续时间延长那些BN有更高的恢复概率。需要使用类似严格的回收标准和方法，用前瞻性数据复制这些结果，以确认趋势。
Objective:To compare patterns of recovery in individuals with index episodes of anorexia nervosa (AN) and bulimia nervosa (BN).Method:Using Kaplan–Meier methods and Cox proportional hazards models, comparisons were conducted that were conditional on duration of eating disorder from onset and included a conservative recovery criterion of 3 asymptomatic years. Data collection was retrospective and from two of the international Price Foundation genetic studies on 901 individuals with eating disorders.Results:Using Kaplan–Meier methods, 11% of those with index AN and 10% of those with index BN met recovery criteria at 10 years. At 15 years, 16% of those with index AN and 25% of those with index BN met recovery criteria. In a Cox proportional hazards model the index BN group had three times the rate of recovery at 10–14 years (p=0.01) than the index AN group.Conclusions:Initially the probability of recovery was greater for those with index AN, but as the duration of the eating disorder lengthened those with BN had higher probabilities of recovery. Replication of these results with prospective data using similarly stringent recovery criteria and methods is required to confirm trends.