The Neuro Bureau ADHD-200 Preprocessed repository
The Neuro Bureau ADHD-200 Preprocessed repository
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DOI：
10.1016/j.neuroimage.2016.06.034
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发表时间：
2017-01-01
期刊：
影响因子：
5.7
通讯作者：
Craddock, R. Cameron
中科院分区：
文献类型：
--
作者：
Bellec, Pierre;Chu, Carlton;Craddock, R. Cameron
2011年，举办了“ADHD-200全球竞赛”，目的是从973人的静息状态功能磁共振成像（rs-IMRI）和结构磁共振成像（s-MRI）数据中确定注意力缺陷/多动障碍的生物标志物。统计学家和计算机科学家可能是最有资格参加机器学习竞赛的人，但他们通常缺乏为rs-IMRI实施必要的数据准备步骤的专业技能。意识到这一进入障碍，神经局前瞻性地与所有竞争对手合作，对数据进行预处理，并在神经影像信息学工具和资源交换所（NITRC）（http：//www.nitrc.org/frspgroup_id=383）共享这些结果。这个“ADHD-200预处理”版本包括多个分析管道，以满足不同的数据分析哲学。处理后的衍生物包括去噪和配准的4D fMRI体积、从脑包裹提取的区域时间序列、10个内在连接网络的图、低频波动的分数振幅和区域均匀性，以及沿着灰质密度图。参加ADHD-200全球竞赛的几个团队使用了这些数据，其中包括一组生物统计学家的获奖作品。据我们所知，ADHD-200 Preprocessed版本是第一个预处理静息态fMRI和结构MRI数据的大型公共资源，并且直到今天仍然是唯一具有替代处理路径的资源。(C)2016 Elsevier Inc. All rights reserved.
In 2011, the "ADHD-200 Global Competition" was held with the aim of identifying biomarkers of attentiondeficit/hyperactivity disorder from resting-state functional magnetic resonance imaging (rs-IMRI) and structural MRI (s-MRI) data collected on 973 individuals. Statisticians and computer scientists were potentially the most qualified for the machine learning aspect of the competition, but generally lacked the specialized skills to implement the necessary steps of data preparation for rs-IMRI. Realizing this barrier to entry, the Neuro Bureau prospectively collaborated with all competitors by preprocessing the data and sharing these results at the Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC) (http:// www.nitrc.org/frspgroup_id=383). This "ADHD-200 Preprocessed" release included multiple analytical pipelines to cater to different philosophies of data analysis. The processed derivatives included denoised and registered 4D fMRI volumes, regional time series extracted from brain parcellations, maps of 10 intrinsic connectivity networks, fractional amplitude of low frequency fluctuation, and regional homogeneity, along with grey matter density maps. The data was used by several teams who competed in the ADHD-200 Global Competition, including the winning entry by a group of biostaticians. To the best of our knowledge, the ADHD-200 Preprocessed release was the first large public resource of preprocessed resting-state fMRI and structural MRI data, and remains to this day the only resource featuring a battery of alternative processing paths. (C) 2016 Elsevier Inc. All rights reserved.