A randomized controlled trial of auricular acupuncture for cocaine dependence
A randomized controlled trial of auricular acupuncture for cocaine dependence
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DOI：
10.1001/archinte.160.15.2305
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发表时间：
2000-08-14
影响因子：
--
通讯作者：
Kosten, TR
中科院分区：
文献类型：
--
作者：
Avants, SK;Margolin, A;Kosten, TR
Background: Partly because of a lack of a conventional, effective treatment for cocaine addiction, auricular acupuncture is used to treat this disorder in numerous drug treatment facilities across the country for both primary cocaine-dependent and opiate-dependent populations.Objective: To evaluate the effectiveness of auricular acupuncture for the treatment of cocaine addiction.Methods: Eighty-two cocaine-dependent, methadone-maintained patients were randomly assigned to 1 of 3 conditions: auricular acupuncture, a needle-insertion control condition, or a no-needle relaxation control. Treatment sessions were provided 5 times weekly for 8 weeks. The primary outcome was cocaine use assessed by 3-times-weekly urine toxicology screens.Results: Longitudinal analysis of the urine data for the intent-to-treat sample showed that patients assigned to acupuncture were significantly more likely to protide cocaine-negative urine samples relative to both the relaxation control (odds ratio, 3.41; 95% confidence interval, 1.33-8.72; P=.01) and the needle-insertion control (odds ratio, 2.40; 95% confidence interval, 1.00-5.75; P=.05).Conclusions: Findings from the current study suggest that acupuncture shows promise for the treatment of cocaine dependence. Further investigation of this treatment modality appears to be warranted.
