Ventricular volume and mass by CMR
Ventricular volume and mass by CMR
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DOI：
10.1081/jcmr-120016389
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发表时间：
2002-01-01
影响因子：
6.4
通讯作者：
Pennell, DJ
中科院分区：
文献类型：
--
作者：
Pennell, DJ
心血管磁共振（Cardiovascular magnetic resonance，CMR）是一种理想的心血管系统检查技术，它具有心肌、血池和肺的高分辨力鉴别、无X射线、无创等优点。这与高水平的准确性[1-4]和可重复性[5-9]相结合，使其在心室体积和质量评估的研究竞技场中非常受欢迎。伦理委员会毫不犹豫地批准了这种扫描，并且需要少量的患者来证明诸如新药对重塑的影响等假设。[10 CMR现在被认为是这种测量的黄金标准。[12]将CMR应用于评估心室大小和质量（容量法）的技术已经开发了多年，早期的方法已经被丢弃，因为它们牺牲了速度的质量，这在我们现代享受的快速扫描环境中是不必要的。因此，将不再考虑横轴平面中的单层或多层自旋回波技术[13]或采用几何假设的单层和双层长轴电影技术[14]。获得广泛认可的技术是短轴多层（多个2D或3D）电影采集，其中从房室环到心尖对两个心室进行采样，随后对心室的心内膜和心外膜边界进行平面测量，以获得所需的体积和质量参数。通过这种方法获得的体积是独立的几何假设，这是一个主要的优势，在1D和2D超声心动图技术。在这篇文章中描述了这种技术，商定的命名和显示平面的心脏是同意联合出版的指南。[15，16]
Cardiovascular magnetic resonance (CMR) is an ideal technique for investigating the cardiovascular system, because it has excellent high resolution differentiation of myocardium from blood pool and lung, and is free from xrays and noninvasive. This combined with high levels of accuracy,[1–4] and reproducibility,[5–9] has made it very popular in the research arena for the assessment of ventricular volumes and mass. Ethical committees approve such scans with little hesitation, and small patient numbers are needed to prove hypotheses such as the effect of a new drug on remodeling.[10, 11] CMR is now considered the gold standard for such measurements.[12] The techniques for applying CMR to the problem of assessing ventricular size and mass (volumetry) have been developed over many years, and earlier methods have been discarded because they compromised quality for speed, something which is not necessary in the fast scanning environment we enjoy in modern times. Thus, single or multislice spin echo techniques in the transaxial plane,[13] or single and dual long axis cine techniques adopting geometric assumptions,[14] will not be considered further. The technique that has won widespread acceptance is the short axis multislice (multiple 2D or 3D) cine acquisition, where both ventricles are sampled from the atrioventricular ring to the apex, with subsequent planimetry of the endocardial and epicardial borders of the ventricles to derive the required volume and mass parameters. The volumes obtained by this method are independent of geometric assumptions, which is a major advantage over 1D and 2D echocardiographic techniques. In this article describing this technique, the agreed nomenclature and display of planes of the heart is used as agreed by jointly published guidelines.[15, 16]