SPECIFICITY OF SMOOTH PURSUIT EYE-MOVEMENT AND VISUAL FIXATION ABNORMALITIES IN SCHIZOPHRENIA - COMPARISON TO MANIA AND NORMAL CONTROLS
SPECIFICITY OF SMOOTH PURSUIT EYE-MOVEMENT AND VISUAL FIXATION ABNORMALITIES IN SCHIZOPHRENIA - COMPARISON TO MANIA AND NORMAL CONTROLS
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DOI：
10.1016/0920-9964(91)90040-x
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发表时间：
1991-09-01
影响因子：
4.5
通讯作者：
SCHNUR, D
中科院分区：
文献类型：
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作者：
AMADOR, XF;SACKEIM, HA;SCHNUR, D
对30名精神分裂症患者、12名无锂躁狂患者和20名正常对照进行了平滑追踪眼动（SPEM）评估。与精神分裂症患者相比，躁狂患者在注意增强、正弦目标运动条件下表现出较少的SPEM损伤，在视觉固定条件下表现更好。SPEM和视觉固定功能障碍可能在精神分裂症患者中比在急性躁狂患者中更常见，即使后者以明显的注意力功能障碍、发作间社会心理功能差和精神病为特征。
Smooth pursuit eye movements (SPEM) were assessed in 30 schizophrenic patients, 12 lithium-free manic patients, and 20 normal controls. Compared to schizophrenic patients, manic patients evidenced less SPEM impairment in an attention enhancing, sinusoidal target motion condition and had superior performance during a visual fixation condition. SPEM and visual fixation dysfunctions may be more common in schizophrenic than in acutely manic patients, even when the latter are characterized by marked attentional dysfunction, poor interepisode psychosocial functioning, and psychosis.