Increased incidence of adenocarcinoma of the cervix in young women in the United States.
Increased incidence of adenocarcinoma of the cervix in young women in the United States.
复制标题
美国年轻女性宫颈腺癌的发病率增加。
DOI：
10.1093/oxfordjournals.aje.a114474
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发表时间：
1986
影响因子：
5
通讯作者：
Weiss,NS
中科院分区：
文献类型：
--
作者：
Schwartz,SM;Weiss,NS
这是自 20 世纪 70 年代初以来第二份报告显示年轻白人女性宫颈腺癌的发病率有所增加。这一趋势似乎并不是由于组织学分类随着时间的推移而改善的。显然需要进行病例对照研究来调查增加的原因，包括与 20 岁之前使用口服避孕药的假设相关性。然而，该病在年轻女性中的发病率较低（如果存在的话，最有可能检测到风险增加），这表明即使是适度的样本量也需要共同努力才能实现。
This is the second report demonstrating an increase in the incidence of adenocarcinoma of the cervix in young white women since the early 1970s. The trend does not appear to be due to improved histologic classification over time. Case-control studies are clearly needed to investigate the reasons for the increase, including the hypothesized association with use of oral contraceptives before 20 years of age. However, the low incidence of the disease in young women (in whom an increased risk is most likely to be detectable, should it exist) suggests that collaborative efforts will be required to achieve even modest sample sizes.