Prognostic value of the MIB-1 labeling index for central neurocytomas
Prognostic value of the MIB-1 labeling index for central neurocytomas
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DOI：
10.1212/01.wnl.0000115392.21898.e3
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发表时间：
2004-03-23
期刊：
影响因子：
9.9
通讯作者：
Fehlauer, F
中科院分区：
文献类型：
--
作者：
Rades, D;Schild, SE;Fehlauer, F
尽管中枢神经细胞瘤通常被描述为良性中枢神经系统病变，但也可能发生恶性行为，包括颅脊髓播散和肿瘤相关死亡。本荟萃分析旨在探讨MIB-1标记指数的预后价值。数据不仅来自文献，还来自与作者的接触。数据显示，mb -1指数评分为bb0.3 %与局部对照预后较差（p < 0.0001）和生存率较差（p = 0.0004）相关。
Although central neurocytomas are generally described as benign CNS lesions, malignant behavior including craniospinal dissemination and tumor-related death may occur. This meta-analysis was performed to investigate the prognostic value of the MIB-1 labeling index. Data were obtained not from the literature alone but also from contact with the authors. The data suggested an MIB-1 index score of >3% to be associated with a worse prognosis for local control ( p < 0.0001) and survival ( p = 0.0004).