Cognitive and Neuropsychiatric Impairments in Alzheimer's Disease: Current Treatment Strategies

Cognitive and Neuropsychiatric Impairments in Alzheimer's Disease: Current Treatment Strategies
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DOI:
10.1007/s11920-014-0470-z
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发表时间:
2014-09-01
影响因子:
6.7
通讯作者:
Borson, Soo
Borson, Soo
中科院分区:
医学2区
文献类型:
--
作者:
Borisovskaya, Anna;Pascualy, Marcella;Borson, Soo

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阿尔茨海默病(AD)的这一更新讨论了这种疾病中常见的认知和神经精神症状(如激越,精神病,焦虑和抑郁)的治疗策略,特别强调非药物策略,如认知干预,体育锻炼和心理治疗。我们提供了一个认知增强剂和他们的组合策略和药物常用于治疗AD的神经精神症状的概述。最后,我们提出了建议,为照顾者提供支持,并建议如何确定照顾者/患者对最需要的重症痴呆症护理服务。
This update on Alzheimer's disease (AD) discusses treatment strategies for cognitive and neuropsychiatric symptoms (such as agitation, psychosis, anxiety, and depression) common in this illness, emphasizing in particular nonpharmacologic strategies such as cognitive interventions, physical exercise, and psychotherapy. We provide an overview of cognitive enhancers and their combination strategies and medications commonly used for treatment of neuropsychiatric symptoms in AD. Finally, we give recommendations for providing support to caregivers and suggest how to identify caregiver/patient pairs most in need of intensive dementia care services.