Study of Biochemical Markers in Alcoholic Liver Disease: Hospital-Based Case Control Study
Study of Biochemical Markers in Alcoholic Liver Disease: Hospital-Based Case Control Study
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酒精性肝病生化标志物研究：以医院为基础的病例对照研究
DOI：
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发表时间：
2012
期刊：
影响因子：
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通讯作者：
K. Adhikari
中科院分区：
文献类型：
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作者：
M. Adak;A. Thakur;K. Adhikari
在西方世界，酒精中毒是一种慢性、进行性和潜在的肝病原因，在尼泊尔最为常见。有许多关于酒精性肝病(ALD)的生化和血液学指标的数据，但在尼泊尔背景下进行的工作很少。因此，我们努力评估生化标记物在尼泊尔受试者中的地位。ALD患者中男性110例(66.27%)，女性56例(33.73%)。ALD患者的体重显著低于ALD患者(p<0.01)。ALD患者的Hb百分比和RBC总数显著降低，平均红细胞体积(MCV)显著升高。本研究的结果与以前的研究结果一致，表明肝细胞损伤导致这些酶泄漏到循环中。这项研究得出的结论是生化和血液学参数
Alcoholism is a chronic, progressive and potential cause of liver disease in the western world and it is most common in Nepal. Numerous data are available regarding alcoholic liver disease (ALD) with biochemical and hematologic indicators but very few works have been made in the Nepalese context. Hence, an effort has been made to evaluate the status of biochemical markers in ALD among the Nepalese subjects.166 ALD cases were enrolled in our OPD. Out of total ALD patients, 110 (66.27 %) patients were male and 56 (33.73%) patients were female. ALD patients had significantly low body weight (p 1 were found with ALD patients respectively. The percentage of hemoglobin and total number of RBC were found to be significantly decreased, whereas mean corpuscular volume (MCV) significantly increased in ALD. The findings of the present study are consistent with previous studies, suggesting that hepatocytes damage causes leak of these enzymes into the circulation. This study concludes that biochemical and hematological parameters is