Photoacoustic mammography capable of simultaneously acquiring photoacoustic and ultrasound images
Photoacoustic mammography capable of simultaneously acquiring photoacoustic and ultrasound images
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DOI：
10.1117/1.jbo.21.11.116009
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发表时间：
2016-11-01
影响因子：
3.5
通讯作者：
Toi, Masakazu
中科院分区：
文献类型：
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作者：
Asao, Yasufumi;Hashizume, Yohei;Toi, Masakazu
我们已经建立了一个原型光声乳房X光成像系统(PAM-02)，能够同时获取光声(PA)和超声(US)图像。每个PA、US和融合的PA/US图像可以使用US换能器、PA探测器和光学棱镜的扫描模块在乳房的大范围内采集。与我们以前的样机采集的图像相比，PA图像的分辨率提高了2到1 mm。PAM-02的最大扫描区域沿水平轴为90 mm，沿垂直轴为150 mm。在体模实验中，可用深度至少为45毫米。给出了京都大学PAM-02样机在临床研究中应用的一个典型例子，并显示了S因子图像，它被认为是与肿瘤相关血管的血红蛋白饱和度有关的近似参数。我们证实了该系统在解剖学和生物学研究中的适用性。(C)作者。由SPIE出版
We have constructed a prototype photoacoustic mammography system (PAM-02) capable of simultaneously acquiring photoacoustic (PA) and ultrasound (US) images. Each PA, US, and fused PA/US image can be acquired over a wide area of the breast using the scanning module of a US transducer, a PA detector, and optical prisms. The resolution of the PA images exhibits improvement from 2 to 1 mm compared to images acquired using our previous prototype. The maximum scan area of PAM-02 is 90 mm along the horizontal axis and 150 mm along the vertical axis. In a phantom experiment, the available depth was at least 45 mm. A representative example of the application of the PAM-02 prototype in clinical research at Kyoto University is presented and shows S-factor images, which are considered an approximation parameter related to hemoglobin saturation of tumor-related blood vessels. We confirmed the applicability of the system for anatomical and biological research. (C) The Authors. Published by SPIE