Higher 24-h Total Movement Activity Percentile Is Associated with Better Cognitive Performance in U.S. Older Adults.
Higher 24-h Total Movement Activity Percentile Is Associated with Better Cognitive Performance in U.S. Older Adults.
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DOI：
10.1249/mss.0000000000002927
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发表时间：
2022-08-01
影响因子：
4.1
通讯作者：
Pettee Gabriel K
中科院分区：
文献类型：
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作者：
Dooley EE;Palta P;Wolff-Hughes DL;Martinez-Amezcua P;Staudenmayer J;Troiano RP;Pettee Gabriel K
评估腕部佩戴的、基于设备的24小时运动指标与60岁及以上老年人的认知功能和主观认知抱怨的相关性。2011-2012年和2013-2014年全国健康和营养检查调查(NHANES)周期横断面分析。戴在手腕上的GT3X+加速度计捕捉24小时的总运动活动；分析为独立于监视器的运动汇总单元(MIMS-Units)；并根据年龄和性别标准化的百分位数量化到位置。进行了记忆、语言/言语流畅性和执行能力领域的认知测试。生成了特定于测试的认知z分数。主观认知症状包括感觉到的记忆困难和困惑/记忆丧失。分析样本包括2708名美国老年人(69.5±0.2岁，55%为女性，20.9%为非白人)。多因素线性回归分析显示，年龄和性别分别位于第3和第4分位数(第50~74百分位)和第4分位(≥第75百分位数)的儿童在各领域的认知功能z分均高于第1分位数。Logistic回归分析显示，第3和第4分位数报告记忆困难的概率也较低(AOR=0.52，95%CI：0.31~0.89；AOR=0.57，95%CI：0.37~0.88)和混淆/记忆丧失(AOR=0.49，95%CI：0.27~0.91)；AOR=0.49，95%CI：0.27-0.98)。在一个具有代表性的美国老年人样本中，24小时运动总活动量达到或超过其年龄和性别的50%百分位数的人认知功能更强。未来的研究应该考虑24小时内的运动行为对老年人认知健康结果的影响。需要更多的研究，探索MIMS单位与中老年时期的时间使用行为之间的预期关联，这可能会影响不同人群的认知功能。
To assess the association of a wrist-worn, device-based metric of 24-hour movement with cognitive function and subjective cognitive complaints among older adults, ages 60 years and older. Cross-sectional analysis of the 2011-2012 and 2013-2014 National Health and Nutrition Examination Survey (NHANES) cycles. A wrist-worn ActiGraph GT3X+ accelerometer captured total 24-hour movement activity; analyzed as Monitor-Independent Movement Summary units (MIMS-units); and quantified into placement based on an age- and sex- standardized percentile. Cognitive tests in the domains of memory, language/verbal fluency, and executive performance were administered. Test-specific cognitive z-scores were generated. Subjective cognitive complaints included perceived difficulty remembering and confusion/memory loss. The analytical sample included 2,708 U.S. older adults (69.5±0.2 years, 55% female, 20.9% non-White). Multivariable linear regressions revealed those in quartiles 3 (50th-74th percentile) and 4 (≥75th percentile) for their age and sex had higher cognitive function z-scores across all domains compared to those in quartile 1. Logistic regressions demonstrated those in quartiles 3 and 4 also had lower odds of reporting difficulty remembering (AOR=0.52, 95% CI: 0.31-0.89; AOR=0.57, 95% CI: 0.37-0.88) and confusion/memory loss (AOR=0.49, 95% CI: 0.27-0.91; AOR=0.49, 95% CI: 0.27-0.98), respectively, compared to those in quartile 1. In a representative sample of U.S. older adults, higher cognitive functioning occurs among those that perform total 24-hour movement activity at or above the 50th percentile for their age and sex. Future studies should consider movement behaviors across a 24-hour period on cognitive health outcomes in older adults. More research exploring prospective associations of MIMS-units and time-use behaviors across midlife and older adulthood that may affect cognitive functioning across diverse populations is needed.