Effect of Long-Term Intensive Endurance Training on Left Ventricular Structure and Diastolic Function in Prepubertal Children
Effect of Long-Term Intensive Endurance Training on Left Ventricular Structure and Diastolic Function in Prepubertal Children
复制标题
长期强化耐力训练对青春期前儿童左心室结构和舒张功能的影响
DOI：
--
复制
发表时间：
1998
影响因子：
2.5
通讯作者：
P. Guenon
中科院分区：
文献类型：
--
作者：
P. Obert;F. Stecken;D. Courteix;A.;P. Guenon
在儿童中，心脏的解剖和功能，特别是在舒张期，是否能适应耐力训练的事实仍然不确定。因此，本研究旨在评价长期高强度耐力游泳运动对10~11岁儿童心脏结构和功能的影响。研究对象为当地青少年游泳队(S)9名儿童和从一所小学招募的11名儿童作为对照组(C)。游泳者平均训练10-12hxwk(-1)至少2年。所有受试者均按美国超声心动图学会推荐的标准程序进行M型、二维和脉冲多普勒检查。研究是在受试者仰卧的状态下进行的。结果显示，高训练组儿童的左心室内径(S：41.6±-1.6，C：39.0±2.2 mm/m(1/3)表面积，P<；0.01)和左心室质量(S：68+/-7，C：59+/-5g/m~2 SA，P<；0.01)显著增加。而S组与C组在房壁厚度(S：5.2±-0.6，C：5.3±0.6 mm/m(1/3)SA；间隔S：5.8±-0.3，C：5.8±0.4 mm/m(1/3)SA)、左心室收缩功能参数(射血分数S：77.1+/-0.3，C：77.7+/-0.4%；左室壁短轴缩短率(S：38.9+/-3.0，C：39.7+/-4.1%)和舒张期功能参数(E波S：1.04+/-0.12，C：1.07+/-0.16m/S；A波S：0.45+/-0.10，C：0.55+/-0.11m/S)。两组静息心输出量相似(S：3.76+/-0.81，C：3.90+/-0.67 L×min(-1))。然而，与C组相比，S组获得的QC显著低于C组(S：69+/-7，C：83+/-14拍x分钟(-1)，P<；0.01)，而每搏输出量(S：55.2+/-8.0，C：47.5+/-8.5ml，P<；0.05)。因此，这些发现有力地表明，正如以前在成人中所显示的那样，由于高强度的耐力训练，青春期前儿童可以发生几种心脏适应(包括静息性心动过缓、每搏输出量增加和左室内径增大)。然而，我们的结果并未显示青春期前训练对舒张期和收缩功能参数有任何影响。
In children, the fact that cardiac anatomy and function, particularly during the diastolic phase, can adapt to endurance training is still uncertain. Therefore, this study was undertaken to evaluate the effect of a long-term intensive endurance swimming program on the cardiac structure and function of 10-11 year old children. The population consisted of 9 children who belonged to a local youth swimming team (S) and 11 recruited from a primary school to serve as a control group (C). The swimmers had been training on average 10 to 12 h x wk(-1) for at least 2 years. All the subjects were examined by M-mode, 2-dimensional and pulsed-wave Doppler analyses according to standard procedures recommended by the American Society of Echocardiography. Investigations were carried out at rest with the subjects in a supine position. The results showed that highly trained children exhibited significantly higher left ventricular (LV) internal diameter (S: 41.6+/-1.6, C: 39.0+/-2.2 mm/m(1/3) surface area, p<0.01) and LV mass (S: 68+/-7, C: 59+/-5 g/m2 SA, p<0.01). There were, however, no differences between S and C for chamber wall thickness (posterior wall S: 5.2+/-0.6, C: 5.3+/-0.6 mm/m(1/3) SA; septum S: 5.8+/-0.3, C: 5.8+/-0.4 mm/m(1/3) SA), LV systolic function parameters (ejection fraction S: 77.1+/-0.3, C: 77.7+/-0.4%; shortening fraction S: 38.9+/-3.0, C: 39.7+/-4.1%) and the diastolic function parameters, estimated from LV inflow velocitometry (E wave S: 1.04+/-0.12, C: 1.07+/-0.16 m/s; A wave S: 0.45+/-0.10, C: 0.55+/-0.11 m/s). Finally, transaortic Doppler examinations demonstrated similar resting cardiac output (Qc) between both groups (S: 3.76+/-0.81, C: 3.90+/-0.67 l x min(-1)). However, Qc were obtained with significantly lower heart rates (S: 69+/-7, C: 83+/-14 beat x min(-1), P<0.01) and higher stroke volumes (S: 55.2+/-8.0, C: 47.5+/-8.5 ml, P<0.05) in S when compared to C. Thus, these findings strongly suggest that, as has been shown before in adults, several cardiac adaptations (including resting bradycardia, increased stroke volume and enlarged left ventricular internal dimensions) can occur in prepubertal children as a result of intensive endurance training. However, our results did not demonstrate any effects of such training during prepuberty on both diastolic and systolic functions parameters.
影响因子：
37.8
作者：
LEWIS, JF;KUO, LC;QUINONES, MA
通讯作者：
QUINONES, MA
静态和动态运动的慢性训练：心血管适应和运动反应。
影响因子：
20.1
作者：
Longhurst,JC;Kelly,AR;Gonyea,WJ;Mitchell,JH
通讯作者：
Mitchell,JH
心脏对长期运动的适应。
影响因子：
9.1
作者：
Schaible,TF;Scheuer,J
通讯作者：
Scheuer,J