Recent developments in the microbial production of 1,3-propanediol
Recent developments in the microbial production of 1,3-propanediol
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DOI：
10.4155/bfs.13.49
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发表时间：
2013-11
期刊：
影响因子：
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通讯作者：
Ting Tang;F. Qi;Hongjuan Liu;De‐hua Liu
中科院分区：
文献类型：
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作者：
Ting Tang;F. Qi;Hongjuan Liu;De‐hua Liu
1,3-propanediol (PDO) is a valuable chemical monomer to polymerize to polytrimethylene terephthalate with terephthalic acid. Polytrimethylene terephthalate is considered as one kind of prospective new polyester. Production of PDO by microbial fermentation leads to a significantly cost-effective process and decreases nonrenewable resources. This article summarizes the latest developments in the microbial production of PDO, including the selection of high-performance PDO-producing microorganisms, the conversion of crude glycerol derived from biodiesel plants to PDO and different fermentation strategies adopted in the fermentation process. Furthermore, genetic engineering is discussed, a technology that provides a more convenient method to obtain microorganisms with high PDO-producing ability. Microbial production of PDO would directly benefit the environment by reducing the use of fossil fuels and elevating the value of biodiesel production, which has become a hotspot in recent decades.
