The contribution of adrenal and reproductive hormones to the opposing effects of stress on trace conditioning in males versus females.
The contribution of adrenal and reproductive hormones to the opposing effects of stress on trace conditioning in males versus females.
复制标题
肾上腺和生殖激素对压力对男性与女性微量调节的相反影响的贡献。
DOI：
10.1037/0735-7044.115.1.175
复制
发表时间：
2001
影响因子：
1.9
通讯作者：
Shors,TJ
中科院分区：
文献类型：
--
作者：
Wood,GE;Beylin,AV;Shors,TJ
暴露于急性应激体验促进雄性大鼠的经典条件反射，但损害雌性大鼠的条件反射（TJ Shors，C. Lewczyk，M. Paczynski，PR Mathew，& J. Pickett，1998; GE Wood & TJ Shots，1998）。作者报告说，这些影响延伸到跟踪条件反射的营地依赖任务的性能。应激诱导的条件反射在雌性动物中的损害是明显的，应激后立即，24小时和48小时，这取决于发情期的阶段。此外，这种效应可以在几天后通过再次暴露于压力环境而重新激活。皮质酮水平与男性的整体表现相关，但在女性中则不然。与在男性中看到的效果不同，肾上腺切除术并不能阻止女性的应激诱导的调节作用。这些数据表明，暴露于相同的经验可以有相反的影响，男性与女性的学习，这些相反的影响是由不同的激素系统介导的。（PsycInfo数据库记录（c）2016阿帕，保留所有权利）
Exposure to an acute stressful experience facilitates classical conditioning in male rats but impairs conditioning in female rats (TJ Shors, C. Lewczyk, M. Paczynski, PR Mathew, & J. Pickett, 1998; GE Wood & TJ Shots, 1998). The authors report that these effects extend to performance on the hippocampal-dependent task of trace conditioning. The stress-induced impairment of conditioning in females was evident immediately, 24 hr and 48 hr after stress, depending on the stage of estrus. Moreover, the effect could be reactivated days later by reexposure to the stressful context. Corticosterone levels correlated with overall performance in males but not in females. Unlike the effect seen in males, adrenalectomy did not prevent the stress-induced effect on conditioning in females. These data indicate that exposure to the same experience can have opposite effects on learning in males versus females and that these opposing effects are mediated by differing hormonal systems.(PsycINFO Database Record (c) 2016 APA, all rights reserved)