A novel estimation system for multiple pulse echo signals from ultrasound contrast microbubbles
A novel estimation system for multiple pulse echo signals from ultrasound contrast microbubbles
复制标题
一种新颖的超声造影微泡多脉冲回波信号估计系统
DOI：
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发表时间：
2008
期刊：
影响因子：
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通讯作者：
V. Sboros
中科院分区：
文献类型：
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作者：
Yan Yan;J. Hopgood;V. Sboros
对非线性微泡信号的理解和利用是一个活跃的研究领域，旨在将造影剂超声推进到高灵敏度和特异性的诊断成像模式。为了区分组织回波与对比微泡回波的差异，尽可能多地提取反射信号的信息，特别是脉冲在时域的位置及其对应的频域频谱内容，具有重要意义。本文提出了一种新的感兴趣信息提取估计系统。该估计技术基于非参数方法进行粗估计，然后在贝叶斯框架内采用参数方法进行估计精化。结果表明，该方法可以同时准确地估计脉冲位置和频率含量。这有助于在今后的工作中设计发射脉冲体制。
The understanding and exploitation of non-linear microbubble signals is an active research area that aims to advance contrast ultrasound into a high sensitivity and specificity diagnostic imaging modality. To discriminate the difference between echoes from tissue and contrast microbubbles, it is of significance to extract as much information of the reflected signals as possible, especially the pulse locations in the time domain and their corresponding spectral contents in the frequency domain. In this paper, a novel estimation system for extracting the information of interest is proposed. This estimation technique is based on non-parametric methods for coarse estimation, followed by a parametric method within Bayesian framework for estimation refinement. The results show that the pulse location and frequency content can be accurately estimated simultaneously. This assists in the design of transmit pulsing regimes in future work.