METHICILLIN‐RESISTANT STAPHYLOCOCCUS AUREUS BACTERAEMIA
METHICILLIN‐RESISTANT STAPHYLOCOCCUS AUREUS BACTERAEMIA
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DOI：
10.5694/j.1326-5377.1981.tb100894.x
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发表时间：
1981-08
影响因子：
11.4
通讯作者：
M. McDonald;A. Hurse;Kwang N. Sim
中科院分区：
文献类型：
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作者：
M. McDonald;A. Hurse;Kwang N. Sim
在墨尔本皇家医院两年期间发生的53例医院获得性葡萄球菌菌血症中，有28例(53%)是由耐甲氧西林金黄色葡萄球菌(MRSA)引起的。每个患有MRSA菌血症的患者都有易患医院内败血症的重要基础条件，而且每个患者当时都有血管内异物。大多数人在医院的特殊护理区域接受护理，并在出现菌血症之前的一个月内接触过多种或广谱抗生素。感染MRSA的患者应该被隔离，当考虑到菌血症的诊断时，任何潜在的主要病灶都应该被移除。万古霉素是危及生命的耐甲氧西林金黄色葡萄球菌感染的首选药物。
Twenty‐eight (53%) of 53 hospital‐acquired staphylococcal bacteraemias which occurred at The Royal Melbourne Hospital over a two‐year period were due to methicillin‐resistant Staphylococcus aureus (MRSA). Every patient with MRSA bacteraemia had a significant underlying condition predisposing to nosocomial sepsis, and each had an intravascular foreign body in situ at the time. Most were being nursed in special care areas of the hospital and had been exposed to multiple or broad‐spectrum antibiotics during the month before development of bacteraemia. Patients acquiring MRSA infection should be isolated and, when the diagnosis of bacteraemia is considered, any potential primary focus should be removed. Vancomycin is the drug of choice in life‐threatening MRSA infections.