New clinical color threshold test for eye disease.
New clinical color threshold test for eye disease.
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眼部疾病的新临床颜色阈值测试。
DOI：
10.1097/00006324-198701000-00005
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Huie,K
中科院分区：
文献类型：
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作者：
Adams,AJ;Schefrin,B;Huie,K
当蓝光被短波长敏感的视锥细胞（B视锥细胞）检测到时，对蓝光的敏感性的选择性丧失是许多视网膜和视觉通路疾病的常见早期征兆。需要可靠的临床试验来检测这种缺陷。我们描述了一种新的，简单的强制选择临床测试的B锥功能，这是简单，可靠的，和免费的病人标准看到。测试结果相对不受高达2D的未矫正屈光不正和患者在测试期间通常的小固定变化的影响。三个不同的测试结果的比较，都是在5分钟内获得的，允许测量R和/或G视锥细胞功能，而不受年龄和由B视锥细胞测试结果中的眼介质变黄引起的个体差异的影响。该试验已被用于证明B视锥细胞敏感性损失与60例糖尿病患者视网膜病变的严重程度相关，以及青光眼和高眼压症的选择性B视锥细胞损失。
Selective loss of sensitivity to blue light, when it is detected by the short wavelength-sensitive cones (B cones), is a common early sign of many retinal and visual pathway disorders. A reliable clinical test is needed to allow detection of this defect. We describe a new, simple forced-choice clinical test of B cone function which is brief, reliable, and free of patient criteria for seeing. Test results are relatively unaltered by up to 2 D of uncorrected refractive error and the usual small fixation changes the patient makes during the test. A comparison of three different test results, all obtained within 5 min, allows measurement of R and/or G cone function free of age and individual differences caused by yellowing of the ocular media in the B cone test result. The test has been used to demonstrate B cone sensitivity losses related to the severity of retinopathy in 60 diabetics, as well as selective B cone loss in glaucoma and ocular hypertension.