Clinical neurophysiology laboratory tests to assess the nociceptive system in humans
Clinical neurophysiology laboratory tests to assess the nociceptive system in humans
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DOI：
10.1097/00004691-199701000-00003
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发表时间：
1997-01-01
影响因子：
2.4
通讯作者：
Dotson, RM
中科院分区：
文献类型：
--
作者：
Dotson, RM
本文介绍了一些目前可用的神经生理学工具，这些工具有助于在临床环境中评估和记录可能与疼痛相关的神经性障碍，本文讨论的具体测试包括定量感觉测试（QSTs）、自主神经测试（ATs）、微神经造影（MCNG）和激光诱发电位（LEPs）。痛觉系统的定量感觉测试包括热刺激（TST）和当前感知阈值（CPT）测试。适用于部分疼痛患者的ATs是舒缩试验和血管舒缩试验。定量sudomotor轴突反射测试（QSART）、静息排汗量（RSO）和交感皮肤反应（SSR）是sudomotor受累的测试。血管舒张系统是通过在静止状态下测量皮肤温度（表面热敏电阻或热成像）来测试的，在某些情况下，在刺激性动作之后。此外，MCNG（单神经纤维或神经束的神经内记录）允许检查人员直接观察肌肉和皮肤的交感神经传出输出，这些输出是在没有疼痛或实验性疼痛的正常受试者和神经性疼痛患者中进行的。这项技术也为研究神经性疼痛患者的初级传入纤维的生理学提供了一种手段。最近发展的lep结合了使用疼痛的红外激光诱导刺激，可以选择性地研究伤害系统，包括中央和外周部分。
This paper presents some currently available neurophysiological tools that are helpful in the clinical setting to evaluate and document neuropathic disturbances that may be associated with pain, The specific tests described in this discussion are quantitative sensory tests (QSTs), autonomic tests (ATs), microneurography (MCNG), and laser evoked potentials (LEPs). Quantitative sensory testing of the nociceptive system includes the thermal stimulation (TST) and current perception threshold (CPT) tests. The ATs applicable to some patients with pain are sudomotor and vasomotor tests. The quantitative sudomotor axon reflex test (QSART), resting sweat output (RSO), and sympathetic skin response (SSR) are the tests for sudomotor involvement. The vasomotor system is tested by measuring skin temperature (surface thermistor or thermography) at rest and, in some cases, after provocative maneuvers, In addition, MCNG (intraneural recording of single nerve fibers or fascicles of nerves) allows examiners to look directly at muscle and skin sympathetic efferent output in normal subjects without pain or with experimental pain and in patients with neuropathic pain. This technique also provides a means of studying the physiology of primary afferent fibers in persons with neurogenic pain. Recent development of LEPs that incorporate the use of painful infrared laser-induced stimuli allow selective study of the nociceptive system, both the central and peripheral portions.