Adenoid hypertrophy in children with allergic disease and influential factors
Adenoid hypertrophy in children with allergic disease and influential factors
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DOI：
10.1016/j.ijporl.2015.02.017
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发表时间：
2015-05-01
影响因子：
1.5
通讯作者：
Nepesov, Merve Iseri
中科院分区：
文献类型：
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作者：
Evcimik, Muhammed Fatih;Dogru, Mahmut;Nepesov, Merve Iseri
目的：腺样体肥大（AH）可能导致多种共病，包括睡眠呼吸暂停、慢性浆液性中耳炎和鼻窦炎。这种情况在患有过敏性疾病的儿童中更为常见。在我们的研究中，我们的目的是确定与腺样体肥大的发病率较高的患者档案和相关的影响factors.Methods：该研究包括1322名儿童正在接受治疗和随访的过敏性疾病。同期门诊就诊的100例无过敏性疾病的儿童作为对照组。对所有患者进行相同变应原的皮肤点刺试验。腺样体组织进行了分析，由耳鼻喉科专家和诊断确诊的基础上，患者的病史，内窥镜体检和放射学。结果：的患者，765（57.9%）是男性和557（42.1%）是女性，他们的平均年龄为5.9 +/- 3.3岁。在对照组中，56名（56%）儿童为男性，44名（44%）为女性，平均年龄为6.3 ± 4.1岁。患有过敏性疾病的儿童和对照组在年龄和性别上没有显著差异。在164例（12.4%）过敏性疾病患者和3例（3%）对照组中发现腺样体肥大。过敏儿童被分为两组，分别为有和无AH的儿童。各组在性别、年龄或特应性疾病家族史方面没有统计学显著差异。然而，在AH患者组中，家中暴露于香烟烟雾和过敏性鼻炎的发生率明显更高。在调查变量对AH存在的影响的逻辑模型中（根据年龄、性别、香烟烟雾暴露、哮喘、AR、AD存在、特应性存在、对室内灰尘、花粉、上皮、链格孢菌和蟑螂的敏感性），AR存在和香烟烟雾暴露在统计学上是显著的。AH患者对过敏原最常见的敏感性是室内灰尘。存在过敏性鼻炎和香烟烟雾暴露是发展AH的危险因素。有这些危险因素的儿童应在常规检查中询问AH。(C)2015爱思唯尔爱尔兰有限公司版权所有。
Objectives: Adenoid hypertrophy (AH) may cause several comorbid conditions including sleep apnea, chronic serous otitis and sinusitis. Such conditions are more common among children with allergic diseases. In our study, we aimed to determine the patient profile associated with higher incidence of adenoid hypertrophy and the related influential factors.Methods: The study included 1322 children being treated and followed up for allergic conditions. 100 children with no allergic diseases presenting during the same period to the clinic were included as the control group. Skin prick test for the same allergens was performed for all patients. Adenoid tissue was analyzed by an ENT specialist and the diagnosis was confirmed based on the patient history, endoscopic physical examination and radiology.Results: Of the patients, 765 (57.9%) were males and 557 (42.1%) were females and their mean age was 5.9 +/- 3.3 years. In the control group, 56(56%) children were males and 44(44%) were females and their mean age was 6.3 +/- 4.1 years. Children with allergic disease and control subjects did not differ significantly by age and gender. Adenoid hypertrophy was identified in 164(12.4%) of the patients with allergic disease and in 3 (3%) of the controls. Allergic children were divided into two groups, as children with and without AH, respectively. The groups did not differ statistically significantly by gender, age or familial history of atopic disease. However, cigarette smoke exposure at home and presence of allergic rhinitis was significantly more frequent in the group of patients with AH. In the logistic model investigating the effect of variables on AH presence (according to age, gender, cigarette smoke exposure, asthma, AR, AD presence, atopy presence, sensitivity to house dust, pollen, epithelium, Alternaria alternata and cockroach), AR presence and cigarette smoke exposure were statistically significant.Contusions: AM frequency is higher in children with allergic disease compared to controls. The most common sensitivity to allergens among patients with AH was to house dust. Presence of allergic rhinitis and cigarette smoke exposure are risk factors for developing AH. Children with these risk factors should be questioned for AH during their routine examinations. (C) 2015 Elsevier Ireland Ltd. All rights reserved.