The prevalence of rheumatoid arthritis in middle-aged and elderly people living in Naqu City, Tibet, Autonomous Region of China
The prevalence of rheumatoid arthritis in middle-aged and elderly people living in Naqu City, Tibet, Autonomous Region of China
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DOI：
10.1186/s13018-020-01883-4
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发表时间：
2020-08-18
影响因子：
2.6
通讯作者：
Lin, Jianhao
中科院分区：
文献类型：
--
作者：
Zhang, Qingxi;Liu, Qiang;Lin, Jianhao
我们使用问卷采访了参与者，并测定了类风湿因子（RF）、抗瓜氨酸化蛋白抗体（ACPA）和c反应蛋白（CRP）。本研究中RA的识别是基于2010年美国风湿病学会/欧洲抗风湿病联盟（ACR/EULAR）指南发布的标准。结果782名参与者完成了RA的所有项目。RA的总患病率为4.86%，女性患病率高于男性（7.14% vs. 2.56%,p= 0.005）。RA的年龄标准化患病率为6.30%(95%可信区间（CI） 4.20-8.64%)，男性和女性分别为2.46% （95% CI 1.04%, 4.10%）和9.59% （95% CI 5.93%, 13.77%）。
Objective To estimate the prevalence of rheumatoid arthritis (RA) in the Tibet Autonomous Region (China). Methods A population-based cross-sectional survey was conducted on 1458 residents of Luoma Town, Tibet Autonomous Region, who were aged >= 40 years old. We interviewed participants using questionnaires, and rheumatoid factor (RF), anti-citrullinated protein antibodies (ACPA), and C-reactive protein (CRP) were determined. The identification of RA in this study was on the basis of criteria issued by the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) guideline. Results Herein, 782 participants completed all items of RA. The overall prevalence of RA was 4.86%, and the prevalence was higher in women than that in men (7.14% vs. 2.56%,p= 0.005). The age-standardized prevalence of RA was 6.30% (95% confidence interval (CI) 4.20-8.64%), which was 2.46% (95% CI 1.04%, 4.10%) and 9.59% (95% CI 5.93%, 13.77%) in men and women, respectively. Conclusion The prevalence of RA is relatively higher in the Tibet than that in other areas of China.