Translating Developmental Neuroscience to Substance Use Prevention.
Translating Developmental Neuroscience to Substance Use Prevention.
复制标题
将发育神经科学转化为药物使用预防。
DOI：
10.1007/s40429-015-0050-2
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发表时间：
2015
影响因子：
4.3
通讯作者：
Riggs,NathanielR
中科院分区：
文献类型：
--
作者：
Riggs,NathanielR
一些预防性干预措施已证明在减少药物使用方面是有效的。然而，存在进一步改进预防办法的机会。发展神经科学的最新进展的应用可以为物质使用预防计划的设计，实施和评估提供信息。本文首先简要介绍了前额叶皮层与大脑的情绪和动机中心的发展整合，以及这一过程对物质使用脆弱性的影响。接下来讨论的是发育神经科学如何为预防时机、发育和评估提供信息的具体例子。然后提出了背景考虑因素，包括学校在预防药物滥用方面的关键作用。最后，目前的理论和方法的挑战，发展神经科学物质使用预防的翻译进行了讨论。
Several preventive interventions have demonstrated efficacy in reducing substance use. However, opportunities exist to further improve prevention approaches. The application of recent advances in developmental neuroscience can inform the design, implementation, and evaluation of substance use prevention programs. This paper first briefly describes the developmental integration of the prefrontal cortex with emotion and motivation centers of the brain, and the implications of this process for substance use vulnerability. Discussed next are specific examples of how developmental neuroscience can inform prevention timing, development, and evaluation. Contextual considerations are then suggested including a critical role for schools in substance misuse prevention. Finally, current theoretical and methodological challenges to the translation of developmental neuroscience to substance use prevention are discussed.