Recruitment of Healthy First-Trimester Pregnant Women: Lessons From the Chemicals, Health & Pregnancy Study (CHirP)
Recruitment of Healthy First-Trimester Pregnant Women: Lessons From the Chemicals, Health & Pregnancy Study (CHirP)
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DOI：
10.1007/s10995-010-0739-8
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发表时间：
2012-02-01
影响因子：
2.3
通讯作者：
Janssen, Patricia A.
中科院分区：
文献类型：
--
作者：
Webster, Glenys M.;Teschke, Kay;Janssen, Patricia A.
描述和评估用于招募152名怀孕不到15周的健康孕妇参加怀孕期间环境化学品暴露的前瞻性研究的招募技术。海报、网站、在线和印刷广告、招聘电子邮件、媒体报道、从诊所候诊室招聘、与怀孕社区建立联系，以及在婴儿“贸易展”上展示研究摊位，这些都被用来宣传这项研究。参与者必须符合一套严格的资格标准，并被要求捐献妊娠中期的血液样本，完成两份调查问卷，从家中收集空气、灰尘、棉绒和自来水样本，并在分娩时捐献脐带血样本。在17个月的时间里，171名女性参加了这项研究（49%的初次接触者，99%的合格女性），152名女性完成了这项研究（89%的保留率）。每名最终参与者的招募费用总额约为400加元。海报、研究展台展示和在线广告引发了对该研究的最多询问。口口相传、另一项研究的推荐和直接电子邮件是最具成本效益的策略。毫不奇怪，与温哥华孕妇的背景人群相比，招募的研究人群种族多样性较低，更富裕，受教育程度更高。被动和主动招募技术的结合成功地招募了大约怀孕前三个月（< 15周妊娠）的健康妇女。虽然方便的女性样本适合我们的研究问题，但在未来的研究中，可能需要额外的策略来招募更具代表性的孕妇群体。
To describe and evaluate recruitment techniques used to enroll 152 healthy pregnant women fewer than 15 weeks gestation into a prospective study of environmental chemical exposure during pregnancy. Posters, a website, online and print advertising, recruitment emails, media coverage, recruitment from clinic waiting rooms, networking within the pregnancy community and presenting a study booth at baby "trade shows" were used to advertise the study. Participants had to meet a strict set of eligibility criteria, and were asked to donate two-second-trimester blood samples, complete two questionnaires, have samples of air, dust, lint and tap water collected from their homes, and donate a cord blood sample at delivery. Over 17 months, 171 women enrolled (49% of initial contacts, and 99% of all eligible women) and 152 women completed the study (89% retention). Total recruitment costs were approximately $400 Cdn per final participant. Posters, study booth presentations and online advertising generated the most inquiries about the study. Word of mouth, referral from another study and direct email were the most cost-effective strategies. Not surprisingly, the recruited study population was less ethnically diverse, more affluent and more educated than the background population of pregnant women in Vancouver. A combination of passive and active recruitment techniques were successful for recruiting healthy women in roughly the first trimester of pregnancy (< 15 weeks gestation). While a convenience sample of women is suitable for our study questions, additional strategies may be required to recruit a more representative pregnant population in future studies.