Contagious itch in humans: a study of visual 'transmission' of itch in atopic dermatitis and healthy subjects.
Contagious itch in humans: a study of visual 'transmission' of itch in atopic dermatitis and healthy subjects.
复制标题
DOI：
10.1111/j.1365-2133.2011.10318.x
复制
发表时间：
2011-06
期刊：
影响因子：
--
通讯作者：
Yosipovitch G
中科院分区：
文献类型：
--
作者：
Papoiu AD;Wang H;Coghill RC;Chan YH;Yosipovitch G
轶事证据表明，“传染性”瘙痒发生在日常生活中，当我们看到其他人发痒和抓挠。这种现象以前没有被系统地研究过，并且可以放大瘙痒感知的因素是未知的。我们研究了在健康和特应性皮炎受试者中暴露于瘙痒的视觉线索是否会诱发或加剧瘙痒。参与者接受了组织胺或盐水控制输送到前臂，并被要求观看人们抓挠的短视频剪辑。监测和分析由视觉线索引起的自发抓挠。特应性皮炎患者报告了更高的瘙痒强度，并且在观看瘙痒视频时更频繁地抓挠，即使在存在模拟瘙痒刺激的情况下。人类暴露于视觉线索时对瘙痒的易感性得到了证实，并且在特应性皮炎患者中似乎被放大了。这些发现表明，人际社会线索可以显着改变主观感觉经验的瘙痒。
Anecdotal evidence suggests “contagious” itch occurs in daily life when we see other people itch and scratch. This phenomenon has not been systematically studied previously, and factors which can amplify itch perception were unknown. We investigated whether exposure to visual cues of itch can induce or intensify itch in healthy and atopic dermatitis subjects. Participants received histamine or a saline control delivered to the forearm and were asked to watch short video clips of people scratching. Spontaneous scratching induced by visual cues was monitored and analyzed. Atopic dermatitis patients reported a higher itch intensity and scratched more frequently while watching itch videos, even in the presence of mock itch stimuli. Human susceptibility to develop itch when exposed to visual cues is confirmed and it appears amplified in atopic dermatitis sufferers. These findings suggest that interpersonal social cues can dramatically alter the subjective sensory experience of itch.