A prospective study of fish, marine fatty acids, and bladder cancer risk among men and women (United States)
A prospective study of fish, marine fatty acids, and bladder cancer risk among men and women (United States)
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DOI：
10.1007/s10552-006-0059-x
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发表时间：
2006-11-01
影响因子：
2.3
通讯作者：
Michaud, Dominique S.
中科院分区：
文献类型：
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作者：
Holick, Crystal N.;Giovannucci, Edward L.;Michaud, Dominique S.
目的前瞻性评价健康专业人员跟踪研究和护士健康研究两个队列中鱼类、海洋脂肪酸的摄入量与膀胱癌风险的关系。COX比例风险模型被用来估计鱼摄入量和膀胱癌风险之间的发病率比(RR)和95%可信区间(CI)，调整了年龄、总卡路里摄入量、吸烟年限和当前吸烟。结果我们没有观察到总体上鱼摄入量和膀胱癌风险之间存在显著的相关性，即使当我们比较->=每天1份鱼和鱼摄入量=每天1份鱼
Objective To evaluate prospectively the association between intakes of fish, marine fatty acids, and bladder cancer risk in two ongoing cohorts, the Health Professionals Follow-up Study and the Nurses' Health Study.Methods During 16 and 18 years of follow-up, 501 and 235 incident cases of bladder cancer were diagnosed among men and women, respectively. Cox proportional hazard models were used to estimate incidence rate ratios (RR) and 95% confidence intervals (CI) between fish intake and bladder cancer risk adjusting for age, total caloric intake, pack-years of cigarette smoking, and current smoking.Results We observed no significant overall association between total fish intake and bladder cancer risk, even when we compared >= 1 servings of fish per day to fish intake = 1 total fish servings per day compared to