The effects of various definitions of dipping and daytime and night-time on the characterization of 24 h profiles of blood pressure.
The effects of various definitions of dipping and daytime and night-time on the characterization of 24 h profiles of blood pressure.
复制标题
不同的浸渍定义以及白天和夜间对 24 小时血压曲线特征的影响。
DOI：
10.1097/00126097-200002000-00004
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
Tuhrim,S
中科院分区：
文献类型：
--
作者：
Butkevich,A;Phillips,RA;Sheinart,KF;Tuhrim,S
工作背景：动态血压监测允许表征患者的平均血压负荷以及各种血压曲线。临床研究结果表明，杓型患者（夜间血压下降的患者）发生心血管事件的风险低于白天血压相似的非杓型患者。然而，在临床研究中，对血压下降的定义以及白天和夜间的定义各不相同。目的：为了确定不同的定义是否会导致对血压下降状态的显著不同的分类。设计和方法：我们分析了894个24小时动态血压记录，这些记录是根据之前发表的三个白天和夜间的定义以及五个血压下降的定义在我们机构进行的。结果：使用不同定义测定的平均日间和夜间血压之间存在较小但具有统计学意义的差异。同样，比例的dippers变化与定义的浸渍和白天和夜间time.Conclusions：浸渍的定义之间的差异，以及白天和夜间导致显着变化的患者的24小时血压曲线的特征。该分析的结果可用于比较临床研究的结果及其设计。
Background: Ambulatory blood pressure monitoring allows characterization of the patient's average blood pressure load as well as various profiles of blood pressure. Results from clinical studies suggest that dippers (patients whose blood pressures decrease during night-time) have a lower risk of cardiovascular events than do nondippers with similar daytime blood pressures. However, the definitions of dipping as well as of daytime and night-time vary among clinical studies.Objective: To determine whether various definitions lead to markedly different classifications of dipper status.Design and methods: We analyzed 894 24 h ambulatory blood pressure recordings that had been performed at our institution according to three previously published definitions of daytime and night-time and five definitions of dipping.Results: There were small but statistically significant differences among the mean daytime and night-time blood pressures determined using the various definitions. Likewise, the proportions of dippers varied significantly with definitions of dipping and of daytime and night-time.Conclusions: Differences among definitions of dipping as well as of daytime and night-time lead to significant variations in the characterization of patients' 24 h blood blood pressure profiles. The results of this analysis can be used when comparing the results of clinical studies as well as in their design.