Consensus statement from the 2014 International Microdialysis Forum.

Consensus statement from the 2014 International Microdialysis Forum.
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DOI:
10.1007/s00134-015-3930-y
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发表时间:
2015-09
影响因子:
38.9
通讯作者:
Ungerstedt U
Ungerstedt U
中科院分区:
医学1区
文献类型:
--
作者:
Hutchinson PJ;Jalloh I;Helmy A;Carpenter KL;Rostami E;Bellander BM;Boutelle MG;Chen JW;Claassen J;Dahyot-Fizelier C;Enblad P;Gallagher CN;Helbok R;Hillered L;Le Roux PD;Magnoni S;Mangat HS;Menon DK;Nordström CH;O'Phelan KH;Oddo M;Perez Barcena J;Robertson C;Ronne-Engström E;Sahuquillo J;Smith M;Stocchetti N;Belli A;Carpenter TA;Coles JP;Czosnyka M;Dizdar N;Goodman JC;Gupta AK;Nielsen TH;Marklund N;Montcriol A;O'Connell MT;Poca MA;Sarrafzadeh A;Shannon RJ;Skjøth-Rasmussen J;Smielewski P;Stover JF;Timofeev I;Vespa P;Zavala E;Ungerstedt U

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微透析使细胞外间隙的化学被监测。在急性脑损伤患者中使用这种技术增加了我们对几种急性神经系统疾病的病理生理学的理解。2004年,发表了关于脑微透析临床应用的共识文件。从那时起,微透析在神经重症监护中的临床应用取得了重大进展。本综述的目的是报告2014年4月在英国剑桥举行的国际微透析论坛,并就其临床应用(包括技术、数据解释、与结局的关系、在神经重症监护和研究应用中指导治疗的作用)提出修订和更新的共识声明。本文的在线版本(doi:10.1007/s 00134 -015-3930-y)包含补充材料,可供授权用户使用。
Microdialysis enables the chemistry of the extracellular interstitial space to be monitored. Use of this technique in patients with acute brain injury has increased our understanding of the pathophysiology of several acute neurological disorders. In 2004, a consensus document on the clinical application of cerebral microdialysis was published. Since then, there have been significant advances in the clinical use of microdialysis in neurocritical care. The objective of this review is to report on the International Microdialysis Forum held in Cambridge, UK, in April 2014 and to produce a revised and updated consensus statement about its clinical use including technique, data interpretation, relationship with outcome, role in guiding therapy in neurocritical care and research applications. The online version of this article (doi:10.1007/s00134-015-3930-y) contains supplementary material, which is available to authorized users.