Inductively heated shape memory polymer for the magnetic actuation of medical devices
Inductively heated shape memory polymer for the magnetic actuation of medical devices
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DOI：
10.1109/tbme.2006.877113
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发表时间：
2006-10-01
影响因子：
4.6
通讯作者：
Maitland, Duncan J.
中科院分区：
文献类型：
--
作者：
Buckley, Patrick R.;McKinley, Gareth H.;Maitland, Duncan J.
目前，人们对利用形状记忆聚合物（SMP）制造可扩展支架和血管内微致动器等医疗器械很感兴趣。实现SNIP医疗设备的关键挑战之一是在体内实现一种安全有效的热驱动各种设备几何形状的方法。提出了一种新型的居里热调节感应加热驱动方案，在空气中通过交变磁场感应加热驱动镍锌铁氧体铁磁颗粒制成的SNIP原型医疗器械。采用动态力学热分析方法对颗粒加载和整齐SMP材料进行分析，以评估铁素体颗粒对样品力学性能的影响。量热法用于量化SNIP中铁素体颗粒大小和体积负荷的产热率。这些试验证明了感应加热驱动SMP的可行性。在复杂的器件几何形状中实现了快速均匀的加热，并且高达10%体积含量的颗粒加载不会干扰SMP的形状恢复。
Presently, there is interest in making medical devices such as expandable stents and intravascular microactuators from shape memory polymer (SMP). One of the key challenges in realizing SNIP medical devices is the implementation of a safe and effective method of thermally actuating various device geometries in vivo. A novel scheme of actuation by Curie-thermoregulated inductive heating is presented Prototype medical devices made from SNIP loaded with nickel zinc ferrite ferromagnetic particles were actuated in air by applying an alternating magnetic field to induce heating. Dynamic mechanical thermal analysis was performed on both the particle-loaded and neat SMP materials to assess the impact of the ferrite particles on the mechanical properties of the samples. Calorimetry was used to quantify the rate of heat generation as a function of particle size and volumetric loading of ferrite particles in the SNIP. These tests demonstrated the feasibility of SMP actuation by inductive heating. Rapid and uniform heating was achieved in complex device geometries and particle loading up to 10% volume content did not interfere with the shape recovery of the SMP.