The anterobithorax and bithorax mutations of the bithorax complex.
The anterobithorax and bithorax mutations of the bithorax complex.
复制标题
双胸复合体的前胸和双胸突变。
DOI:
10.1002/j.1460-2075.1986.tb04497.x
复制
发表时间:
1986
期刊:
影响因子:
--
通讯作者:
W. Bender
中科院分区:
文献类型:
--
作者:
M. Peifer;W. Bender
The anterobithorax (abx) and bithorax (bx) genes together direct the development of the posterior second and anterior third thoracic segments of the fruit fly. We have characterized the phenotypes and DNA lesions of 19 abx and bx alleles. abx and bx mutations differ both in the nature and location of their DNA lesions, forming two clusters within a relatively small region of the Ultrabithorax transcription unit. Correlation between phenotype and DNA lesion suggests the presence of two or more genetic elements in this region distinct from the Ultrabithorax transcript. Mutant transformations do not strictly obey segmental or parasegmental boundaries. Most of the bx mutations result from insertions of the mobile element gypsy. The strength of these alleles varies in a regular way dependent on the position and orientation of the gypsy element. We propose models for gypsy element action and bithorax complex expression in the light of these results.
DOI:
--
发表时间:
1982
期刊:
Progress in clinical and biological research
影响因子:
--
作者:
Lewis,EB
通讯作者:
Lewis,EB