Rat chromosome 1: regional localization of seven genes (Slc9a3, Srd5a1, Esr, Tcp1, Grik5, Tnnt3, Jak2) and anchoring of the genetic linkage map to the cytogenetic map.

Rat chromosome 1: regional localization of seven genes (Slc9a3, Srd5a1, Esr, Tcp1, Grik5, Tnnt3, Jak2) and anchoring of the genetic linkage map to the cytogenetic map.
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大鼠染色体 1:七个基因(Slc9a3、Srd5a1、Esr、Tcp1、Grik5、Tnnt3、Jak2)的区域定位,并将遗传连锁图锚定到细胞遗传学图。

DOI:
10.1007/s003359900532
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发表时间:
1997
期刊:
Mammalian genome : official journal of the International Mammalian Genome Society
影响因子:
--
通讯作者:
Levan,G
Levan,G
中科院分区:
--
文献类型:
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作者:
Szpirer,C;Szpirer,J;Tissir,F;Stephanova,E;Vanvooren,P;Kurtz,TW;Iwai,N;Inagami,T;Pravenec,M;Kren,V;Klinga-Levan,K;Levan,G

文献摘要

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Seven genes were regionally localized on rat Chromosome (Chr) 1, from 1p11 to 1q42, and two of these genes were also included in a linkage map. This mapping work integrates the genetic linkage map and the cytogenetic map, and allows us to orient the linkage map with respect to the centromere, and to deduce the approximate position of the centromere in the linkage map. These mapping data also indicate that theSlc9a3gene, encoding the Na+/H+exchanger 3, is an unlikely candidate for the blood pressure loci assigned to rat Chr 1. These new localizations expand comparative mapping between rat Chr 1 and mouse or human chromosomes.