A Lethal Case of Sphingomonas paucimobilis Bacteremia in an Immunocompromised Patient.
A Lethal Case of Sphingomonas paucimobilis Bacteremia in an Immunocompromised Patient.
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DOI：
10.1155/2016/3294639
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发表时间：
2016
影响因子：
1.1
通讯作者：
Kurniawan A
中科院分区：
文献类型：
--
作者：
Hardjo Lugito NP;Cucunawangsih;Kurniawan A
少动鞘氨醇单胞菌是一种黄色、葡萄糖非发酵、需氧、革兰氏阴性、低致病性的芽孢杆菌。在留置导管植入、无菌静脉注射液或受污染的医院环境（如自来水和蒸馏水、雾化器、呼吸机和血液透析设备）中发现该微生物。一名55岁女性因糖尿病足溃疡住院，存在多种合并症：糖尿病、结肠结核、终末期肾病和中心静脉导管和血液透析留置导管。患者在入院第44天死于感染性休克。入院第29天血培养发现的微生物为多药耐药S。少动的严重感染和感染性休克。特别是在免疫功能低下的患者中，已经报道了少动症，但是只有一例感染性休克的早产儿死亡的报道。这是第一例报道的致死性S。成人少动杆菌菌血症。
Sphingomonas paucimobilis is a yellow-pigmented, glucose nonfermenting, aerobic, Gram negative bacillus of low pathogenicity. This organism was found in the implantation of indwelling catheters, sterile intravenous fluid, or contaminated hospital environment such as tap and distilled water, nebulizer, ventilator, and hemodialysis device. A 55-year-old female was hospitalized for diabetic foot ulcer in the presence of multiple comorbidities: diabetes mellitus, colonic tuberculosis, end-stage renal disease, and indwelling catheters for central venous catheter and hemodialysis. The patient passed away on the 44th day of admission due to septic shock. The organism found on blood culture on the 29th day of admission was multidrug resistant S. paucimobilis. Severe infection and septic shock due to S. paucimobilis have been reported particularly in immunocompromised patients, but there has been only one reported case of death in a premature neonate with septic shock. This is the first reported lethal case of S. paucimobilis bacteremia in an adult patient.