EFFECT OF SLEEP DISRUPTION ON SLEEP, PERFORMANCE, AND MOOD
EFFECT OF SLEEP DISRUPTION ON SLEEP, PERFORMANCE, AND MOOD
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DOI：
10.1093/sleep/8.1.11
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发表时间：
1985-01-01
期刊：
影响因子：
5.6
通讯作者：
BONNET, MH
中科院分区：
文献类型：
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作者：
BONNET, MH
11名年轻成人受试者在不受干扰的实验室适应和基线夜晚后，连续2个晚上在脑电图定义的睡眠后每分钟短暂醒来。两个不受干扰的恢复之夜之后中断之夜。在中断的夜晚，受试者被听力计唤醒，并通过睡眠状态或按钮按压反应的主观评级来发出唤醒的信号。中断程序导致严重的碎片化睡眠，只有非常少量的慢波和REM睡眠。每晚总睡眠时间减少约1小时。唤醒阈值增加了56分贝整个中断的夜晚。中断后，受试者表现更差，并认为自己比基线更困倦。下降的水平与40-64小时的总睡眠丧失期后观察到的相似。恢复睡眠也类似于完全睡眠丧失后的睡眠。结论是，周期性的睡眠中断，可能通过破坏睡眠的连续性，很快导致功能受损。这些数据可能有助于解释严重睡眠呼吸暂停患者的功能丧失。
Eleven young adult subjects were briefly awakened after each minute of electroencephalographic-defined sleep for 2 consecutive nights after undisturbed laboratory adaptation and baseline nights. Two undisturbed recovery nights followed disruption nights. On disruption nights, subjects were awakened with an audiometer and signaled the awakening by subjective rating of sleep state or button push response. The disruption procedure resulted in severely fragmented sleep with only very small amounts of slow-wave and REM sleep. Total sleep time was reduced by approximately 1 h on each night. Arousal threshold increased 56 dB across the disruption nights. Following disruption, subjects performed more poorly and rated themselves sleepier than on baseline. The level of decline was similar to that seen after periods of total sleep loss of 40–64 h. Recovery sleep was also similar to that seen after total sleep loss. It was concluded that periodic disruption of sleep, perhaps by destroying sleep continuity, quickly results in impaired function. These data may help explain function loss in severe sleep apneics.