Somatosensory evoked potentials for the prognosis of coma in humans
Somatosensory evoked potentials for the prognosis of coma in humans
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体感诱发电位对人类昏迷的预后
DOI：
10.1016/0014-4886(78)90085-7
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发表时间：
1978
影响因子：
5.3
通讯作者：
J. W. Surgeon
中科院分区：
文献类型：
--
作者：
J. C. Torre;J. Trimble;Raquel T. Beard;K. Hanlon;J. W. Surgeon
对17例闭合性颅脑损伤昏迷患者进行了双侧半球体感诱发电位(SEP)检测。对74名正常志愿者进行对照诱发电位测试。根据SEP分析，所有17名患者都做出了可能恢复或无法从昏迷中恢复的预后。所有受试者都接受了双侧正中神经和腓神经刺激，并通过放置在手腕和腿部躯体感觉皮质上的头皮电极来计算反应的平均值。根据SEP分析，所有17名患者的预后都得到了准确的预测。结果显示，在17例预后为“阳性恢复”的患者中，有4例在300ms的时基分析中出现了8个明确的SEP峰。12例预后为“阴性恢复”的患者在500ms的时间基础上出现了5个或更少的SEP峰值。大多数“恢复正常”的患者只有SEP初级波形成分，由两个峰组成。这些数据提出了一种潜在的有用的方法，使用SEP分析来预测临床昏迷的可能恢复。
Studies of bilateral hemispheric somatosensory evoked potentials (SEP) were carried out on 17 comatose patients following closed-head injury. Control evoked potentials were obtained from 74 normal volunteers. A prognosis of potential recovery or nonrecovery from coma was made in all 17 patients based on the SEP analyses. All subjects underwent bilateral median and peroneal nerve stimulation and responses were averaged from scalp electrodes placed over the somatotopic sensory cortex for the wrist and leg. The prognostic outcome of all 17 patients was accurately predicted following SEP analysis. Results show that 4 of 17 patients with prognoses of “positive recovery” had eight defined SEP peaks present within a time base analysis of 300 ms. Twelve patients with prognoses of “negative recovery” had five or less SEP peaks present within a time base of 500 ms. The majority of the “negative recovery” patients showed only SEP primary waveform components consisting of two peaks. The data suggest a potentially useful method using SEP analysis to prognosticate the possible recovery from clinical coma.