The genetic variability of polygenic characters under optimizing selection, mutation and drift.
The genetic variability of polygenic characters under optimizing selection, mutation and drift.
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优化选择、突变和漂移下多基因性状的遗传变异。
DOI：
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发表时间：
1972
期刊：
影响因子：
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通讯作者：
M. Bulmer
中科院分区：
文献类型：
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作者：
M. Bulmer
从理论上探讨了优化选择、突变和漂移对由多个效应相等的无显性位点决定的度量性状的影响。在没有漂移的情况下，在选择和突变下的稳定平衡的条件已经获得，因此可以通过突变维持的遗传变异性的量已经确定。在有限大小的群体中存在漂移时，预期遗传变异的平均量的近似表达式也已获得和评估。
The effect of optimizing selection, mutation and drift on a metric character determined by a large number of loci with equal effects without dominance was investigated theoretically. Conditions for a stable equilibrium under selection and mutation, in the absence of drift, have been obtained, and hence the amount of genetic variability which can be maintained by mutation has been determined. An approximate expression for the average amount of genetic variability to be expected in the presence of drift in a population of finite size has also been obtained and evaluated.