Efficacy of Repetitive Transcranial Magnetic Stimulation (rTMS) for Tinnitus: A Retrospective Study
Efficacy of Repetitive Transcranial Magnetic Stimulation (rTMS) for Tinnitus: A Retrospective Study
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DOI：
10.1177/01455613211016896
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发表时间：
2021-06
期刊：
影响因子：
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通讯作者：
Haidi Yang;Gui Cheng;Zhengrong Liang;Wenting Deng;Xiayin Huang;Minqian Gao;Yiqing Zheng
中科院分区：
文献类型：
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作者：
Haidi Yang;Gui Cheng;Zhengrong Liang;Wenting Deng;Xiayin Huang;Minqian Gao;Yiqing Zheng
目的：目前的研究仍然没有足够的证据支持常规使用重复经颅磁刺激（rTMS）治疗耳鸣。本研究旨在评估耳鸣对rTMS治疗的反应，并确定影响整体反应的因素。研究方法：在2016年1月至2017年5月期间，从孙逸仙纪念医院的电子病历回顾性审查中确定了199名耳鸣患者。所有患者均接受rTMS治疗。提取他们的临床人口学特征和结局，包括耳鸣障碍量表（THI）和视觉模拟量表（VAS）评分进行分析。结果：关于THI结果，62.3%的患者对rTMS有反应。VAS评分分析显示总缓解率为66.3%。这两个百分比都接近患者的主观评估结果，为63.8%。耳鸣持续时间小于1周的患者在THI/VAS评分或患者症状的主观评估方面对rTMS的应答率最高。耳鸣持续时间被认为是影响治疗总体反应的一个因素。结论：重复经颅磁刺激治疗耳鸣有效，但疗效受耳鸣持续时间的影响。建议耳鸣患者尽快接受rTMS治疗，因为治疗对病程短于1周的患者更有效。
Objective: Current studies still find insufficient evidence to support the routine use of repetitive transcranial magnetic stimulation (rTMS) in tinnitus. This study aimed to assess response of tinnitus to treatment with rTMS and identify factors influencing the overall response. Methods: Between January 2016 and May 2017, 199 tinnitus patients were identified from a retrospective review of the electronic patient record at the Sun Yat-sen Memorial Hospital. All patients received rTMS treatment. Their clinicodemographic profile and outcomes, including the tinnitus handicap inventory (THI) and visual analog scale (VAS) scores, were extracted for analysis. Results: Regarding the THI results, 62.3% of all patients responded to rTMS. The analysis of the VAS score revealed an overall response rate of 66.3%. Both percentages were close to the patient’s subjective assessment result, of 63.8%. Patients with tinnitus of less than 1-week duration had the highest response rate to rTMS in terms of either THI/VAS scores or the patient’s subjective assessment of symptoms. Tinnitus duration was recognized as a factor influencing the overall response to the treatment. Conclusions: Repetitive transcranial magnetic stimulation treatment is effective for patients with tinnitus, but its efficacy is affected by tinnitus duration. Tinnitus patients are advised to attend for rTMS as soon as possible since therapy was more effective in those with a shorter duration of disease of less than 1 week.