ATHEROSCLEROSIS AND ANEURYSM OF AORTA IN RELATION TO SMOKING-HABITS AND AGE
ATHEROSCLEROSIS AND ANEURYSM OF AORTA IN RELATION TO SMOKING-HABITS AND AGE
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DOI：
10.1378/chest.78.6.805
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发表时间：
1980-01-01
期刊：
影响因子：
9.6
通讯作者：
GARFINKEL, L
中科院分区：
文献类型：
--
作者：
AUERBACH, O;GARFINKEL, L
在一项对1965年至1970年从男性患者尸检中收集的1412例动脉粥样硬化病变的研究中，发现了动脉粥样硬化病变程度、吸烟习惯和年龄之间的直接关系。使用斑块形成、溃疡和钙化的分级系统记录病变的程度。这些发现随着吸烟数量的增加而增加，并且在戒烟者和烟斗或雪茄吸烟者中比非吸烟者更大。腹主动脉的改变比胸主动脉更广泛。每天吸烟1 - 2包香烟的人比不吸烟的人发生动脉瘤的频率高8倍。与白色受试者相比，黑人受试者的动脉瘤数量约为1/2，广泛动脉粥样硬化病变较少。在年龄超过65岁的人群中，腹主动脉瘤发生率为11%，重度吸烟者为16%。
A direct relationship between the extent of atherosclerotic lesions, smoking habits and age was found in a study of 1412 aortas collected at autopsy from male patients from 1965 to 1970. The extent of the lesions was recorded using grading systems for formation of plaques, ulceration and calcification. These findings increased with the number of cigarettes smoked and were greater in ex-cigarette smokers and pipe or cigar smokers than in nonsmokers. More extensive alterations were found in the abdominal aorta than in the thoracic aorta. Aneurysms were found 8 times more frequently among those smoking 1 to 2 packs of cigarettes/day than in nonsmokers. Black subjects showed about 1/2 the number of aneurysms and fewer extensive atherosclerotic lesions than white subjects. At ages over 65 yr, abdominal aortic aneurysms were found in 11% of all men and in 16% of the heavy smokers.