Dopant-controlled synthesis of water-soluble hexagonal NaYF4 nanorods with efficient upconversion fluorescence for multicolor bioimaging
Dopant-controlled synthesis of water-soluble hexagonal NaYF4 nanorods with efficient upconversion fluorescence for multicolor bioimaging
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DOI：
10.1007/s12274-010-1008-2
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发表时间：
2010-03
期刊：
影响因子：
9.9
通讯作者：
Xuefeng Yu;Min Li;Meng-Yin Xie;Liang-dong Chen;Yan Li;Ququan Wang
中科院分区：
文献类型：
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作者：
Xuefeng Yu;Min Li;Meng-Yin Xie;Liang-dong Chen;Yan Li;Ququan Wang
提出了一种通过掺杂大离子半径稀土离子（La3+、Ce3+、Pr3+、Nd3+、Sm3+、Eu3+、Gd3+）直接合成水溶性六方纳米棒的新策略，并对掺杂控制生长机理进行了研究。基于掺杂效应，制备了水溶性六方纳米棒NaYF4:(Yb,Er)/La和NaYF4:(Yb,Er)/Ce，其上转换荧光比相应的立方形式更亮。通过改变掺杂剂的浓度和反应时间，纳米棒的尺寸可以在很大的范围内调整。此外，我们成功地利用合成的NaYF4:(Yb,Er)/La纳米棒作为探针，展示了一种新的深度敏感的多色病毒生物成像。
A novel strategy is proposed to directly synthesize water-soluble hexagonal NaYF4nanorods by doping rare-earth ions with large ionic radius (such as La3+, Ce3+, Pr3+, Nd3+, Sm3+, Eu3+, and Gd3+), and the dopantcontrolled growth mechanism is studied. Based on the doping effect, we fabricated water-soluble hexagonal NaYF4:(Yb,Er)/La and NaYF4:(Yb,Er)/Ce nanorods, which exhibited much brighter upconversion fluorescence than the corresponding cubic forms. The sizes of the nanorods can be adjusted over a broad range by changing the dopant concentration and reaction time. Furthermore, we successfully demonstrated a novel depth-sensitive multicolor bioimaging forin vivouse by employing the as-synthesized NaYF4:(Yb,Er)/La nanorods as probes.