Accelerated phase contrast MRI using hybrid one- and two-sided flow encodings only (HOTFEO).
Accelerated phase contrast MRI using hybrid one- and two-sided flow encodings only (HOTFEO).
复制标题
仅使用混合一侧和两侧流编码 (HOTFEO) 的加速相差 MRI。
DOI：
10.1002/nbm.3904
复制
发表时间：
2018
影响因子：
2.9
通讯作者：
Hu,Peng
中科院分区：
文献类型：
--
作者：
Wang,Da;Chien,Aichi;Shao,Jiaxin;Ali,FadilAbbas;Hu,Peng
本工作的目的是开发和评估一种仅采用单侧和双侧血流编码(HOTFEO)的快速相位对比磁共振成像(PC-MRI)技术，用于精确测量三维速度编码PC-MRI的血流和速度。四维(4D)PC-MRI以交错方式获取流动补偿(FC)和三向流动编码(FE)回波。我们假设血流速度方向(而不是大小)在两个连续的心脏时相之间有最小的变化。这一假设提供了一个速度方向约束，使用三个方向的有限元数据来计算FC数据而不是获取它们，可以实现4/3倍的加速。HOTFEO捕获模式可以解决病态约束，提高计算精度。对健康志愿者进行HOTFEO检查，并与常规二维(2D)和4D血流成像技术(FC/3FE)和三维FE扫描(FC/3FE)进行比较。与FC/3FE相比，Bland-Altman试验显示，4/3倍的加速HOTFEO技术对颈总动脉总流量的偏差相对较小(前瞻性2D数据为0.89%，回顾4D数据为-1.19%，前瞻性4D数据为-3.40%)，最大峰值流速(前瞻性2D数据为0.50%，回顾性4D数据为-0.17%，前瞻性4D数据为-2.00%)。HOTFEO可以加速编码PC-MRI的三个方向的速度，同时保持总体积流量和最大峰值速度的测量精度。
The aim of this work was to develop and evaluate a fast phase contrast magnetic resonance imaging (PC‐MRI) technique with hybrid one‐ and two‐sided flow encodings only (HOTFEO) for accurate blood flow and velocity measurements of three‐directional velocity encoding PC‐MRI. Four‐dimensional (4D) PC‐MRI acquires flow‐compensated (FC) and three‐directional flow‐encoded (FE) echoes in an interleaved fashion. We hypothesize that the blood flow velocitydirection(not magnitude) has minimal change between two consecutive cardiac phases. This assumption provides a velocity direction constraint that can achieve 4/3‐fold acceleration using three‐directional FE data to calculate FC data instead of acquiring them. The HOTFEO acquisition pattern can address the ill‐conditioned constraint and improve the calculation accuracy. HOTFEO was evaluated in healthy volunteers and compared with conventional two‐dimensional (2D) and 4D flow imaging techniques with FC and three‐directional FE acquisitions (FC/3FE). Compared with FC/3FE, Bland–Altman tests showed that the 4/3‐fold accelerated HOTFEO technique resulted in relatively small bias error for total volumetric flow (0.89% for prospective 2D data, –1.19% for retrospective 4D data and –3.40% for prospective 4D data) and maximum peak velocity (0.50% for prospective 2D data, –0.17% for retrospective 4D data and –2.00% for prospective 4D data) measurements in common carotid arteries. HOTFEO can accelerate three‐directional velocity encoding PC‐MRI whilst maintaining the measurement accuracy of the total volumetric flow and maximum peak velocity.