Highly sensitive graphene biosensors based on surface plasmon resonance
Highly sensitive graphene biosensors based on surface plasmon resonance
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DOI：
10.1364/oe.18.014395
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发表时间：
2010-07-05
期刊：
影响因子：
3.8
通讯作者：
Li, E. P.
中科院分区：
文献类型：
--
作者：
Wu, L.;Chu, H. S.;Li, E. P.
提出了一种基于表面等离子体共振（SPR）的石墨烯生物传感器。它由涂覆在金薄膜上的石墨烯片组成，这是最近提出并实验制造的[ChemPhysChem 11，585（2010）]。该传感器利用衰减全反射（ATR）方法检测传感器表面附近的折射率变化，这是由于生物分子的吸附。我们的计算表明，所提出的石墨烯-金SPR生物传感器（具有L个石墨烯层）比传统的金薄膜SPR生物传感器灵敏（1 + 0.025 L）x γ（其中γ> 1）倍。提高的灵敏度是由于石墨烯上生物分子的吸附增加（由因子γ表示）和石墨烯的光学性质。(C)2010年美国光学学会
A surface plasmon resonance (SPR) based graphene biosensor is presented. It consists of a graphene sheet coated above a gold thin film, which has been proposed and experimentally fabricated recently [ChemPhysChem 11, 585 (2010)]. The biosensor uses attenuated total reflection (ATR) method to detect the refractive index change near the sensor surface, which is due to the adsorption of biomolecules. Our calculations show that the proposed graphene-on-gold SPR biosensor (with L graphene layers) is (1 + 0.025 L) x gamma (where gamma > 1) times more sensitive than the conventional gold thin film SPR biosensor. The improved sensitivity is due to increased adsorption of biomolecules on graphene (represented by the factor gamma) and the optical property of graphene. (C) 2010 Optical Society of America