Evaluation of the stability of intracortical microelectrode arrays
Evaluation of the stability of intracortical microelectrode arrays
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DOI：
10.1109/tnsre.2006.870495
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发表时间：
2006-03-01
影响因子：
4.9
通讯作者：
Agnew, WF
中科院分区：
文献类型：
--
作者：
Liu, XD;McCreery, DB;Agnew, WF
为了使用来自大脑的记录的神经活动作为神经假体装置的控制信号，重要的是在长期植入的微电极和神经组织之间保持稳定的界面。我们之前的论文介绍了一种量化记录微电极稳定性的方法。在本文中，该方法是完善1）将刻板的行为模式的尖峰排序程序和2）通过使用基于贝叶斯定理的分类器分配记录的动作电位的底层神经发生器。提出了一种改进的稳定性指标计算方法。不同结构的微电极阵列的稳定性的结果。
In order to use recorded neural activities from the brain as control signals for neuroprosthesis devices, it is important to maintain a stable interface between chronically implanted microelectrodes and neural tissue. Our previous paper introduced a method to quantify the stability of the recording microelectrodes. In this paper, the method is refined 1) by incorporating stereotypical behavioral patterns into the spike sorting program and 2) by using a classifier based on Bayes theorem for assigning the recorded action potentials to the underlying neural generators. An improved method for calculating stability index is proposed. The results for the stability of microelectrode arrays that differ in structure are presented.