Superhydrophobic silver film as a SERS substrate for the detection of uric acid and creatinine

Superhydrophobic silver film as a SERS substrate for the detection of uric acid and creatinine
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超疏水银膜作为SERS基底用于检测尿酸和肌酐

DOI:
10.1364/boe.9.004988
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发表时间:
2018-10-01
影响因子:
3.4
通讯作者:
Feng, Shangyuan
Feng, Shangyuan
中科院分区:
医学2区
文献类型:
--
作者:
Lu, Yudong;Wu, Changji;Feng, Shangyuan

文献摘要

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通过银镜反应和巯基表面功能化制备了超疏水银膜。巯基功能化显著提高了Ag膜的疏水性能(AFS),其接触角值随着巯基烷基链的延伸而略有增加,达到约160度。研究了这些膜的表面增强拉曼散射(Sers)检测能力,AFS-Dodcc是检测R6 G分子的最佳基底,其浓度极限为10(-11)M。将十二烷基硫醇功能化的原子荧光光谱(AFS-Dodec)用于尿酸和肌酐的表面增强拉曼光谱(Sers)检测,在5 ~ 1000 μ M的浓度范围内,拉曼强度与分析物浓度呈良好的线性关系。(C)根据OSA开放获取出版协议的条款,2018年美国光学学会
Superhydrophobic silver films were fabricated by silver-mirror reaction and surface functionalization with thiol. The thiol-functionalization significantly improved the hydrophobic property of the Ag films (AFS), and their contact angle values slightly increased with the extension of a thiol alkyl chain, reaching about 160 degrees. The surface-enhanced Raman scattering (SERS) detection capacity of these films were investigated, and AFS-Dodcc showed the best substrate for R6G molecule detection with the concentration limit of 10(-11) M. AFS functionalized with dodecanethiol (AFS-Dodec) was applied for the SERS detection of uric acid and creatinine, it exhibited good linear dependence relationship between the Raman intensity and analyte concentration in the concentration range of 5 similar to 1000 mu M. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement