Implantable wireless 64-channel system with flexible ECoG electrode and optogenetics probe
Implantable wireless 64-channel system with flexible ECoG electrode and optogenetics probe
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DOI：
10.1109/biocas.2016.7833835
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
S. Yoshimoto;T. Araki;T. Uemura;T. Nezu;T. Sekitani;Takafumi Suzuki;Fumiaki Yoshida;M. Hirata
中科院分区：
文献类型：
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作者：
S. Yoshimoto;T. Araki;T. Uemura;T. Nezu;T. Sekitani;Takafumi Suzuki;Fumiaki Yoshida;M. Hirata
本文介绍了一种具有双通道光遗传学操作的64通道脑电记录系统。所提出的系统，其设计最低限度，使其可植入动物体内，包括主板（75 mm × 40 mm × 12 mm和33.53 g）和模数转换器（ADC）板（25 mm × 20 mm × 2.5 mm和0.98 g）。每个ADC板都有一个8通道24位ADC模块，可以通过软电缆连接到主板。提出了一种用于无创监测的生物相容性和柔性ECoG电极。电极由形状记忆聚合物覆盖，该聚合物在室温（27°C）下是固体，在体温（35°C）下是柔性的。将固体电极插入大脑。由于大脑的温度，电极变得灵活。除了记录通道外，还在柔性聚酰亚胺电缆（50 μm厚和500 μm宽）上开发了两个蓝色和黄色LED，用于光遗传学。本文提出了实验获得的结果表明，该系统记录的大鼠的ECoG与柔性电极和建议的无线系统。
This paper presents a wireless 64-channel electrocorticogram (ECoG) recording system with 2-channel optogenetics manipulation. The proposed system, which is designed minimally to make it implantable into an animal, comprises a main board (75 mm × 40 mm × 12 mm and 33.53 g) and analog-to-digital converter (ADC) boards (25 mm × 20 mm × 2.5 mm and 0.98 g). Each ADC board has an 8-channel 24-bit ADC module that can be connected to the main board with a flexible cable. A biocompatible and flexible ECoG electrode is proposed for non-invasive monitoring. The electrode is covered by shape-memory polymer, which is solid at room temperature (27°C) and flexible at body temperature (35°C). The solid electrode be inserted into a brain. The electrode becomes flexible because of the brain temperature. In addition to the recording channels, two blue and yellow LEDs are developed on a flexible polyimide cable (50 μm thickness and 500 μm width) for optogenetics. This paper presents experimentally obtained results demonstrating that the proposed system records the ECoG of a rat with the flexible electrode and the proposed wireless system.