Delta virus as a vector for the delivery of biologically-active RNAs: possibly a ribozyme specific for chronic hepatitis B virus infection.
Delta virus as a vector for the delivery of biologically-active RNAs: possibly a ribozyme specific for chronic hepatitis B virus infection.
复制标题
Delta 病毒作为传递生物活性 RNA 的载体：可能是一种针对慢性乙型肝炎病毒感染的核酶。
DOI：
10.1007/978-1-4615-3462-4_12
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发表时间：
1992
影响因子：
--
通讯作者：
Taylor,J
中科院分区：
文献类型：
--
作者：
Hsieh,SY;Taylor,J
RNA 种类已被设计为具有特定的生物活性。例子包括反义RNA寡核苷酸（Weintraub等人，1985）和充当内切核糖核酸酶的催化RNA（Haseloff和Gerlach，1988）。最近（Ellington 和 Szostak 1990）开发了一种更通用的方法，允许在试管中选择可以与选定结构域（例如 RNA、DNA 或蛋白质）结合的 RNA 种类。
RNA species have been designed that demonstrate specific biological activities. Examples include the antisense RNA oligonucleotides (Weintraub et al., 1985) and catalytic RNAs that act as endoribonucleases (Haseloff and Gerlach, 1988). And, recently (Ellington and Szostak 1990) have developed an even more general method of allowing the selection, in the test tube, of RNA species that can bind to a chosen domain, for example on an RNA, DNA, or protein.