Oral mucositis.
Oral mucositis.
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DOI：
10.1016/j.cden.2004.07.009
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发表时间：
2005-01-01
影响因子：
--
通讯作者：
Peterson, Douglas E
中科院分区：
文献类型：
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作者：
Lalla, Rajesh V;Peterson, Douglas E
口腔粘膜炎是指口腔粘膜的红斑性、糜烂性和溃疡性病变，见于两种患者群体：(1) 接受涉及口腔领域的放射治疗的头颈癌患者，以及 (2) 接受高剂量癌症化疗的患者。口腔粘膜炎是癌症治疗的一种显着的剂量限制性毒性，具有重要的临床和经济意义。本文回顾了目前关于口腔粘膜炎的发病机制、临床表现、诊断和治疗的知识。
Oral mucositis refers to erythematous, erosive, and ulcerative lesions of the oral mucosa seen in two patient populations: (1) head and neck cancer patients undergoing radiation therapy to fields involving the oral cavity, and (2) patients receiving high-dose chemotherapy for cancer. Oral mucositis is a significant and dose-limiting toxicity of cancer therapy, with important clinical and economic implications. This article reviews the current knowledge on the pathogenesis, clinical presentation, diagnosis, and management of oral mucositis.