Quantifying the reduction in immunoglobulin use over time in patients with chronic immune thrombocytopenic purpura receiving romiplostim (AMG 531)
Quantifying the reduction in immunoglobulin use over time in patients with chronic immune thrombocytopenic purpura receiving romiplostim (AMG 531)
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量化接受 romiplostim (AMG 531) 的慢性免疫性血小板减少性紫癜患者随时间推移免疫球蛋白使用量的减少
DOI：
10.1002/ajh.21463
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发表时间：
2009
影响因子：
12.8
通讯作者：
K. Zervas
中科院分区：
文献类型：
--
作者：
E. Katodritou;Tomas Ganz;E. Terpos;E. Verrou;G. Olbina;V. Gastari;C. Hadjiaggelidou;M. Varthaliti;S. Georgiadou;M. Westerman;K. Zervas
Hepcidin is a liver-derived hormone with a central role in iron regulation and in anemia of inflammation. Its correlations with disease variables, anemia response (AR), and responses to treatment have not been investigated in multiple myeloma (MM). A cohort of anemic MM patients undergoing treatment with immunomodulatory drug (IMiDs)based regimens (n 5 18) or conventional chemotherapy (n 5 16) was studied. Overall, hepcidin decreased significantly between baseline and treatment Cycles 2 and 4 (P 0.05). Twenty-seven patients received erythropoiesis-stimulating agents (ESAs) (14 in the IMiDs group and 13 in the conventional group, P > 0.05) and seven did not. ESAs treatments that have recently been questioned in MM [20] did not show any correlation with AR (P 5 0.1). Baseline and sequential hepcidin values for IMiDs and conventional groups are shown in Fig. 1. Overall, hepcidin showed a statistically
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常见二氢叶酸还原酶 19 碱基对缺失等位基因：早产的新危险因素。
DOI：
10.1093/ajcn/81.3.664
发表时间：
2005
期刊：
The American journal of clinical nutrition
影响因子：
--
作者：
Johnson,WilliamG;Scholl,TheresaO;Spychala,JohnR;Buyske,Steven;Stenroos,EdwardS;Chen,Xinhua
通讯作者：
Chen,Xinhua
影响因子：
20.3
作者：
Kato, GJ;McGcwan, V;Gladwin, MT
通讯作者：
Gladwin, MT
影响因子：
20.3
作者：
Stirewalt, DL;Kopecky, KJ;Radich, JP
通讯作者：
Radich, JP
影响因子：
20.3
作者：
Otake, Yoko;Soundararajan, Sridharan;Fernandes, Daniel J.
通讯作者：
Fernandes, Daniel J.
DOI：
10.1073/pnas.0506612102
发表时间：
2005-09-20
影响因子：
11.1
作者：
Yamada, Y;Jackson-Grusby, L;Jaenisch, R
通讯作者：
Jaenisch, R