Simple Method for Improving the Sensitivity of Functional Near-Infrared Spectroscopy: A Simulation and Phantom Study

Simple Method for Improving the Sensitivity of Functional Near-Infrared Spectroscopy: A Simulation and Phantom Study
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提高功能近红外光谱灵敏度的简单方法:模拟和模型研究

DOI:
10.7567/jjap.52.077001
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发表时间:
2013
影响因子:
1.5
通讯作者:
Takanobu Murayama
Takanobu Murayama
中科院分区:
物理与天体物理4区
文献类型:
--
作者:
K. Fukuda;Kazuaki Koishi;Takanobu Murayama

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为了提高脑组织耗氧量测量的准确性,提出了一种新的功能近红外光谱技术中皮肤血流的消除方法。我们使用两种方法来应用抵消信号。共享孔径方法使用在用于照射光的孔径处检测到的抵消信号,并且附加孔径方法使用在常规测量中的照射孔径和检测孔径之间的中点处检测到的抵消信号。我们应用这些方法,使用一个等边三角形的探头安排。在三角形的中心处检测用于附加孔径方法的抵消信号,并且这种配置减少了探针的数量。通过仿真分析和实验验证了抵消信号的特性。通过一个简单的体模研究证实了本方法的效果。
A novel method for canceling the skin blood flow in functional near-infrared spectroscopy is proposed to improve the accuracy of measurement of oxygen consumption in brain tissue. We use two approaches for applying cancellation signals. The sharing aperture approach uses cancellation signals detected at apertures for irradiating light, and the additional aperture approach uses the cancellation signals detected at the midpoint between the irradiation and detection apertures in the conventional measurement. We apply these methods using an equilateral-triangular probe arrangement. The cancellation signals for the additional aperture approach are detected at the triangle's center and this configuration reduces the number of probes. The characteristics of the cancellation signals are examined by simulation analysis and experiments with a phantom. The effect of the present approach is confirmed with a simple phantom study.
DOI: 10.1364/josaa.11.002727
发表时间: 1994-10-01
影响因子: 1.9
作者:
HASKELL, RC;SVAASAND, LO;TROMBERG, BJ
通讯作者: TROMBERG, BJ