Common and Unique Neural Correlates of Autobiographical Memory and Theory of Mind
Common and Unique Neural Correlates of Autobiographical Memory and Theory of Mind
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DOI：
10.1162/jocn.2009.21344
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发表时间：
2010-06-01
影响因子：
3.2
通讯作者：
Rosenbaum, R. Shayna
中科院分区：
文献类型：
--
作者：
Rabin, Jennifer S.;Gilboa, Asaf;Rosenbaum, R. Shayna
在自传体记忆（AM）中思考个人过去的经历与在心理理论（ToM）中思考他人的心理状态之间的关系存在不一致。 AM 和 ToM 的神经影像学研究一致报告所招募的大脑区域存在重叠。然而，损伤数据表明，患有 AM 损伤的健忘症患者可以拥有完整的 ToM，这表明不同的神经机制支持这些能力 [Rosenbaum, R. S., Stuss, D. T., Levine, B., & Tulving, E. 心理理论独立于情景记忆。科学，318, 1257, 2007]。目前的功能磁共振成像研究检查了记忆自己的经历对个人照片的反应（AM条件）和想象他人的经历对陌生人的照片的反应（ToM条件）的功能和神经相关性。 AM 和 ToM 条件在内容和生动性方面相匹配，并直接与共同基线进行比较。分析显示额叶和颞顶叶区域有共同的活动，但中线结构在 AM 期间表现出更大的活动。对事件构建和细节阐述的更具体分析揭示了 AM 构建过程中右侧海马体的独特激活，以及 ToM 阐述过程中右侧区域（例如右侧颞顶交界处 (TPJ)）的独特激活。此外，左侧海马体/鼻周皮层的一个区域似乎是由事件的生动性驱动的。因此，当使用共同基线并考虑时间动态时，AM 和 ToM 的差异就会出现。此外，ToM 可能需要右侧 TPJ 和相关的外侧区域，而不是海马，因为这种能力在健忘症患者中是完整的。
There is an inconsistency regarding the relationship between thinking about personal past experiences during autobiographical memory (AM) and thinking about other people's mental states during theory of mind (ToM). Neuroimaging studies of AM and ToM consistently report overlap in the brain regions recruited. Lesion data, however, show that amnesic people with AM impairment can have intact ToM, suggesting that distinct neural mechanisms support these abilities [Rosenbaum, R. S., Stuss, D. T., Levine, B., & Tulving, E. Theory of mind is independent of episodic memory. Science, 318, 1257, 2007]. The current fMRI study examined the functional and neural correlates of remembering one's own experiences in response to personal photos (AM condition) and imagining others' experiences in response to strangers' photos (ToM condition). AM and ToM conditions were matched in terms of content and vividness, and were compared directly and to a common baseline. Analyses revealed common activity within frontal and temporal-parietal regions, yet midline structures exhibited greater activity during AM. More specific analyses of event construction and detail elaboration revealed unique activation of the right hippocampus during AM construction, and of lateral regions, such as the right temporo-parietal junction (TPJ) during ToM elaboration. Moreover, a region of left hippocampus/perirhinal cortex appeared to be driven by event vividness. Thus, differences in AM and ToM emerge when a common baseline is used and temporal dynamics are taken into account. Furthermore, the right TPJ and related lateral regions, and not the hippocampus, may be needed for ToM, given that this ability is intact in amnesic people.