Naturally Occurring Biodegradable Polymers as the Basis of Chiral Gels for the Distinction of Enantiomers by Partially Oriented Nmr Spectroscopy
Naturally Occurring Biodegradable Polymers as the Basis of Chiral Gels for the Distinction of Enantiomers by Partially Oriented Nmr Spectroscopy
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天然存在的可生物降解聚合物作为手性凝胶的基础，用于通过部分取向核磁共振光谱区分对映体
DOI：
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发表时间：
2011
影响因子：
1.7
通讯作者：
B. Luy
中科院分区：
文献类型：
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作者：
Silke S D Büchler;G. Kummerlöwe;B. Luy
引言在现代高分辨率NMR光谱学中，各向异性参数起着重要作用。它们可以借助液晶中间相或拉伸聚合物凝胶作为所谓的取向介质来测量。生物存在的手性聚合物作为该技术的取向介质特别令人感兴趣，因为它们允许区分对映体。方法利用氘1D和J-BIRDd、X-HSQC NMR实验研究生物大分子对映体的分辨能力，并对现有的生物大分子进行总结。结果明胶被证明是区分D-脯氨酸从L-脯氨酸和旁边已经知道的生物聚合物，结冷胶被引入作为一种新的生物衍生的聚合物，能够部分对齐溶质分子。结论：生物聚合物是一种非常适合作为配向介质的生物聚合物，在许多情况下能够区分对映体。由于不同介质和溶质分子的取向特性不同，相应聚合物的带宽将在未来进一步增加。
Introduction In modern, high resolution NMR spectroscopy, anisotropic parameters play an important role. They can be measured with the help of liquid crystalline mesophases or stretched polymer gels as so-called alignment media. Biologically occurring chiral polymers are of special interest as alignment media for this technique because they allow enantiomers to be distinguished. Methods Biopolymers have been studied by deuterium 1D and J-BIRDd,X-HSQC NMR experiments with respect to their ability to distinguish enantiomers and a summary of existing biopolymers for the task is given. Results Gelatin is shown to distinguish D-proline from L-proline and next to already known biopolymers, gellan gum is introduced as a novel biologically derived polymer that is able to partially align solute molecules. Conclusions Biologically occurring and biodegradable polymers are well suited as alignment media and in many cases are able to distinguish enantiomers. As the orienting properties are different for different media and solute molecules, the bandwidth of corresponding polymers will be further increased in the future.
影响因子：
4.3
作者：
Kummerloewe, Grit;McCord, Elizabeth F.;Luy, Burkhard
通讯作者：
Luy, Burkhard
影响因子：
15
作者：
Cierpicki, T;Bushweller, JH
通讯作者：
Bushweller, JH