Semaphorins and their receptors: novel features of neural guidance molecules.
Semaphorins and their receptors: novel features of neural guidance molecules.
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DOI：
10.2183/pjab.86.611
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Kikutani H
中科院分区：
文献类型：
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作者：
Kumanogoh A;Kikutani H
脑信号蛋白最初被认为是神经系统发育中的轴突导向因子。近年来，它是新兴的，他们也参与各种生物系统，包括生理和病理过程。在这篇综述中，我们主要集中在我们的累积发现的作用，脑信号蛋白及其受体在免疫系统的调节，同时也总结了最近的进展，在心血管系统的背景下。
Semaphorins were originally identified as axon guidance cues involved in the development of the nervous system. In recent years, it is emerging that they also participate in various biological systems, including physiological and pathological processes. In this review, we primarily focus on our cumulative findings for the role of semaphorins and their receptors in the regulation of the immune system, while also summarizing recent progress in the context of cardiovascular system.