The acute and chronic bronchodilator effects of ephedrine in asthmatic patients.
The acute and chronic bronchodilator effects of ephedrine in asthmatic patients.
复制标题
麻黄碱对哮喘患者的急性和慢性支气管扩张作用。
DOI：
10.1111/j.1365-2125.1975.tb00572.x
复制
发表时间：
1975
影响因子：
3.4
通讯作者：
J. Paterson
中科院分区：
文献类型：
--
作者：
C. S. May;M. Pickup;J. Paterson
在8名哮喘患者中，在用麻黄碱（11 mg，每日3次）或1片，每日3次治疗2周后，对单剂量麻黄碱（22 mg）单独给药或复方片剂给药的支气管扩张反应无变化。2在2周的治疗期间，无论是麻黄碱还是复方片剂，肺功能都没有恶化。3支气管扩张所需的血浆麻黄碱浓度存在患者间差异。4茶碱的半衰期在长期服用片剂后没有改变，每天三次，持续2周。
In eight asthmatic patients, there was no change in the bronchodilator response to a single dose of ephedrine (22 mg) given alone or in a compound tablet, after treatment with ephedrine (11 mg three times a day) or one tablet three times a day for 2 weeks. 2 There was no deterioration in lung function during the 2 week treatment period with either ephedrine or the compound tablet. 3 An inter-patient variation was noted in the plasma ephedrine concentraition required for bronchodilatation. 4 The half-life of theophylline did not change after chronic treatment with the tablets, one three times a day for 2 weeks.