GPU-accelerated study of the inertial cavitation threshold in viscoelastic soft tissue using a dual-frequency driving signal.
GPU-accelerated study of the inertial cavitation threshold in viscoelastic soft tissue using a dual-frequency driving signal.
复制标题
使用双频驱动信号的粘弹性软组织中惯性空化阈值的GPU加速研究。
DOI：
10.1016/j.ultsonch.2022.106056
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发表时间：
2022-08
影响因子：
8.4
通讯作者：
Solovchuk, Maxim
中科院分区：
文献类型：
--
作者：
Filonets, Tatiana;Solovchuk, Maxim
关键词：
Large parametric study of inertial cavitation threshold for dual-frequency signal. Significant decrease of the threshold by using optimal dual-frequency signal. Optimal frequencies of dual-frequency signal were found for different viscoelastic media. The optimal dual-frequency signal gives the threshold independent of bubble radius. Impact of elasticity prevails over viscosity for the optimal dual-frequency signal. Inertial cavitation thresholds under two forms of ultrasonic excitation (the single- and dual-frequency ultrasound modes) are studied numerically. The Gilmore–Akulichev model coupled with the Zener viscoelastic model is used to model the bubble dynamics. The threshold pressures are determined with two criteria, one based on the bubble radius and the other on the bubble collapse speed. The threshold behavior is investigated for different initial bubble sizes, acoustic signal modes, frequencies, tissue viscosities, tissue elasticities, and all their combinations. Due to the large number of parameters and their many combinations (around billion for each threshold criterion), all simulations were executed on graphics processing units to speed up the calculations. We used our own code written in the C++ and CUDA C languages. The results obtained demonstrate that using the dual-frequency signal mode can help to reduce the inertial cavitation threshold (in comparison to the single-frequency mode). The criterion based on the bubble size gives a lower threshold than the criterion using the bubble collapse speed. With an increase of the elasticity, the threshold pressure also increases, whereas changing the viscosity has a very small impact on the optimal threshold, unlike the elasticity. A detailed analysis of the optimal ultrasound frequencies for a dual-frequency driving signal found that for viscosities less than Pas, the first optimal frequency, in general, is much smaller than the second optimal frequency, which can reach 1 MHz. However, for high viscosities, both optimal frequencies are similar and varied in the range – MHz. Overall, this study presents a detailed analysis of inertial cavitation in soft tissue under dual-frequency signal excitation. It may be helpful for the further development of different applications of biomedical ultrasound.
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影响因子：
2.4
作者：
Khokhlova, Tatiana D.;Canney, Michael S.;Bailey, Michael R.
通讯作者：
Bailey, Michael R.
影响因子：
1.5
作者：
Choi, Pak-Kon
通讯作者：
Choi, Pak-Kon
多频超声对不同介质中瞬态空化阈值影响的仿真研究
影响因子：
2.7
作者：
Dong, Hu;Zou, Xiao;Qian, Shengyou
通讯作者：
Qian, Shengyou
影响因子：
2.4
作者：
KELLER, JB;MIKSIS, M
通讯作者：
MIKSIS, M
DOI：
10.1121/1.1901757
发表时间：
2005-07-01
期刊：
ACOUSTICS RESEARCH LETTERS ONLINE-ARLO
影响因子：
--
作者：
Church, CC
通讯作者：
Church, CC